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    Timm9 translocase of inner mitochondrial membrane 9 [ Mus musculus (house mouse) ]

    Gene ID: 30056, updated on 22-May-2018

    Summary

    Official Symbol
    Timm9provided by MGI
    Official Full Name
    translocase of inner mitochondrial membrane 9provided by MGI
    Primary source
    MGI:MGI:1353436
    See related
    Ensembl:ENSMUSG00000021079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tim10a; Timm10; 2810011L15Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 12.2), frontal lobe adult (RPKM 9.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Timm9 in Genome Data Viewer
    Location:
    12 C2; 12
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (71123172..71136675, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (72224159..72237662, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene AT rich interactive domain 4A (RBP1-like) Neighboring gene translocase of outer mitochondrial membrane 20-like Neighboring gene predicted gene, 32906 Neighboring gene RIKEN cDNA 2700049A03 gene Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene predicted gene 7959

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chaperone binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    chaperone-mediated protein transport ISO
    Inferred from Sequence Orthology
    more info
     
    protein import into mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein import into mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial intermembrane space protein transporter complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial intermembrane space protein transporter complex ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mitochondrial import inner membrane translocase subunit Tim9
    Names
    translocase of inner mitochondrial membrane 10 homolog
    translocase of inner mitochondrial membrane 9 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024853.1NP_001020024.1  mitochondrial import inner membrane translocase subunit Tim9

      See identical proteins and their annotated locations for NP_001020024.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate exon in the 5' UTR, compared to variant 1. All variants encode the same protein.
      Source sequence(s)
      AC159620, AI848414, DV652207
      Consensus CDS
      CCDS25962.1
      UniProtKB/Swiss-Prot
      Q9WV98
      Conserved Domains (1) summary
      pfam02953
      Location:1067
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    2. NM_001024854.1NP_001020025.1  mitochondrial import inner membrane translocase subunit Tim9

      See identical proteins and their annotated locations for NP_001020025.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two consecutive exons in the 5' UTR, compared to variant 1. All variants encode the same protein.
      Source sequence(s)
      AC159620, AI848414, AK018764
      Consensus CDS
      CCDS25962.1
      UniProtKB/Swiss-Prot
      Q9WV98
      Related
      ENSMUSP00000021486.8, ENSMUST00000021486.9
      Conserved Domains (1) summary
      pfam02953
      Location:1067
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    3. NM_001286203.2NP_001273132.1  mitochondrial import inner membrane translocase subunit Tim9

      See identical proteins and their annotated locations for NP_001273132.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an internal exon in the 5' UTR, compared to variant 1. All variants encode the same protein.
      Source sequence(s)
      AC159620, AF150101, AI848414
      Consensus CDS
      CCDS25962.1
      UniProtKB/Swiss-Prot
      Q9WV98
      Related
      ENSMUSP00000152455.1, ENSMUST00000221559.1
      Conserved Domains (1) summary
      pfam02953
      Location:1067
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    4. NM_013896.3NP_038924.1  mitochondrial import inner membrane translocase subunit Tim9

      See identical proteins and their annotated locations for NP_038924.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript. All variants encode the same protein.
      Source sequence(s)
      AC159620, AI119857, AI848414, CK626183
      Consensus CDS
      CCDS25962.1
      UniProtKB/Swiss-Prot
      Q9WV98
      Related
      ENSMUSP00000126298.1, ENSMUST00000166120.8
      Conserved Domains (1) summary
      pfam02953
      Location:1067
      zf-Tim10_DDP; Tim10/DDP family zinc finger

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      71123172..71136675 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244122.2XP_011242424.1  mitochondrial import inner membrane translocase subunit Tim9 isoform X1

      See identical proteins and their annotated locations for XP_011242424.1

      UniProtKB/Swiss-Prot
      Q9WV98
      Conserved Domains (1) summary
      pfam02953
      Location:1067
      zf-Tim10_DDP; Tim10/DDP family zinc finger
    2. XM_017315088.1XP_017170577.1  mitochondrial import inner membrane translocase subunit Tim9 isoform X1

      UniProtKB/Swiss-Prot
      Q9WV98
      Conserved Domains (1) summary
      pfam02953
      Location:1067
      zf-Tim10_DDP; Tim10/DDP family zinc finger
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