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    ARL10 ADP ribosylation factor like GTPase 10 [ Homo sapiens (human) ]

    Gene ID: 285598, updated on 6-Sep-2022

    Summary

    Official Symbol
    ARL10provided by HGNC
    Official Full Name
    ADP ribosylation factor like GTPase 10provided by HGNC
    Primary source
    HGNC:HGNC:22042
    See related
    Ensembl:ENSG00000175414 AllianceGenome:HGNC:22042
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ARL10A
    Summary
    Predicted to enable GTP binding activity and GTPase activity. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in brain (RPKM 2.9), ovary (RPKM 2.2) and 22 other tissues See more
    Orthologs
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    Genomic context

    See ARL10 in Genome Data Viewer
    Location:
    5q35.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (176365487..176415063)
    110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (176909834..176926271)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (175792490..175808912)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene SUMO interacting motifs containing 1 Neighboring gene BRCA1/BRCA2-containing complex subunit 3 pseudogene 1 Neighboring gene KIAA1191 Neighboring gene microRNA 1271 Neighboring gene NOP16 nucleolar protein Neighboring gene HIG1 hypoxia inducible domain family member 2A Neighboring gene clathrin light chain B Neighboring gene uncharacterized LOC124901142 Neighboring gene Fas associated factor family member 2 Neighboring gene uncharacterized LOC124901143 Neighboring gene ring finger protein 44

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ39249

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ADP-ribosylation factor-like protein 10
    Names
    ADP-ribosylation factor-like 10A
    ADP-ribosylation factor-like membrane-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001317948.2NP_001304877.1  ADP-ribosylation factor-like protein 10 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC138956, BC059361
      UniProtKB/TrEMBL
      Q6PCE2
      Conserved Domains (1) summary
      cd04162
      Location:79250
      Arl9_Arfrp2_like; Arf-like 9 (Arl9)/Arfrp2-like GTPase
    2. NM_173664.6NP_775935.1  ADP-ribosylation factor-like protein 10 isoform 2

      See identical proteins and their annotated locations for NP_775935.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR compared to variant 1. The encoded isoform (2) has a distinct, shorter C-terminus than isoform 1.
      Source sequence(s)
      AC138956, BC059361, DR001833
      Consensus CDS
      CCDS4400.1
      UniProtKB/Swiss-Prot
      Q8N8L6
      UniProtKB/TrEMBL
      Q6PCE2
      Related
      ENSP00000308496.5, ENST00000310389.6
      Conserved Domains (2) summary
      cd04162
      Location:79237
      Arl9_Arfrp2_like; Arf-like 9 (Arl9)/Arfrp2-like GTPase
      pfam00071
      Location:80218
      Ras; Ras family

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      176365487..176415063
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011534529.4XP_011532831.1  ADP-ribosylation factor-like protein 10 isoform X1

      Conserved Domains (1) summary
      cl21455
      Location:79187
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    2. XM_011534530.4XP_011532832.1  ADP-ribosylation factor-like protein 10 isoform X2

      Conserved Domains (1) summary
      cl21455
      Location:79190
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    3. XM_011534531.4XP_011532833.1  ADP-ribosylation factor-like protein 10 isoform X3

      Conserved Domains (1) summary
      cl21455
      Location:79188
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      176909834..176926271
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)