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    Nsun2 NOL1/NOP2/Sun domain family member 2 [ Mus musculus (house mouse) ]

    Gene ID: 28114, updated on 6-Sep-2021

    Summary

    Official Symbol
    Nsun2provided by MGI
    Official Full Name
    NOL1/NOP2/Sun domain family member 2provided by MGI
    Primary source
    MGI:MGI:107252
    See related
    Ensembl:ENSMUSG00000021595
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mi; Misu; D13Wsu123e
    Expression
    Ubiquitous expression in liver E14 (RPKM 24.0), testis adult (RPKM 23.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nsun2 in Genome Data Viewer
    Location:
    13 B3; 13 35.55 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (69760135..69783899)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (69612016..69635780)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (69750895..69774658)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RAB geranylgeranyl transferase, b subunit pseudogene Neighboring gene steroid 5 alpha-reductase 1 Neighboring gene importin 7 pseudogene Neighboring gene predicted gene, 52059

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA (cytidine-5-)-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA (cytidine-5-)-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables tRNA (cytosine-5-)-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables tRNA (cytosine-5-)-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables tRNA (cytosine-5-)-methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables tRNA (cytosine-5-)-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within hair follicle maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in hair follicle maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mRNA methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mRNA methylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in meiotic cell cycle checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of mRNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of stem cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in tRNA methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in tRNA methylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in tRNA methylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatoid body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular exosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    RNA cytosine C(5)-methyltransferase NSUN2
    Names
    Myc-induced SUN domain containing protein
    NOL1/NOP2/Sun domain family 2
    mRNA cytosine C(5)-methyltransferase
    myc-induced SUN domain-containing protein
    tRNA (cytosine(34)-C(5))-methyltransferase
    tRNA (cytosine-5-)-methyltransferase NSUN2
    tRNA cytosine C(5)-methyltransferase
    NP_663329.3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145354.5NP_663329.3  RNA cytosine C(5)-methyltransferase NSUN2

      See identical proteins and their annotated locations for NP_663329.3

      Status: VALIDATED

      Source sequence(s)
      AI787627, AK030124, BX630130, CJ092700
      Consensus CDS
      CCDS36722.2
      UniProtKB/Swiss-Prot
      Q1HFZ0
      Related
      ENSMUSP00000105321.5, ENSMUST00000109699.11
      Conserved Domains (1) summary
      COG0144
      Location:28430
      RsmB; 16S rRNA C967 or C1407 C5-methylase, RsmB/RsmF family [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      69760135..69783899
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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