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    Nsun2 NOL1/NOP2/Sun domain family member 2 [ Mus musculus (house mouse) ]

    Gene ID: 28114, updated on 9-Sep-2018

    Summary

    Official Symbol
    Nsun2provided by MGI
    Official Full Name
    NOL1/NOP2/Sun domain family member 2provided by MGI
    Primary source
    MGI:MGI:107252
    See related
    Ensembl:ENSMUSG00000021595 Vega:OTTMUSG00000024575
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Misu; D13Wsu123e
    Expression
    Ubiquitous expression in liver E14 (RPKM 24.0), testis adult (RPKM 23.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Nsun2 in Genome Data Viewer
    Location:
    13 C1; 13 35.55 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (69612016..69635780)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (69750895..69774658)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40992 Neighboring gene RAB geranylgeranyl transferase, b subunit pseudogene Neighboring gene steroid 5 alpha-reductase 1 Neighboring gene importin 7 pseudogene Neighboring gene SET domain, bifurcated 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    tRNA (cytosine-5-)-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    tRNA (cytosine-5-)-methyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    hair follicle maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic cell cycle checkpoint IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    tRNA methylation ISO
    Inferred from Sequence Orthology
    more info
     
    tRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    chromatoid body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    tRNA (cytosine(34)-C(5))-methyltransferase
    Names
    Myc-induced SUN domain containing protein
    NOL1/NOP2/Sun domain family 2
    myc-induced SUN domain-containing protein
    tRNA (cytosine-5-)-methyltransferase NSUN2
    NP_663329.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145354.5NP_663329.3  tRNA (cytosine(34)-C(5))-methyltransferase

      See identical proteins and their annotated locations for NP_663329.3

      Status: VALIDATED

      Source sequence(s)
      AI787627, AK030124, BX630130, CJ092700
      Consensus CDS
      CCDS36722.2
      UniProtKB/Swiss-Prot
      Q1HFZ0
      Related
      ENSMUSP00000105321.4, OTTMUSP00000043252, ENSMUST00000109699.10, OTTMUST00000060366
      Conserved Domains (2) summary
      TIGR00446
      Location:78429
      nop2p; NOL1/NOP2/sun family putative RNA methylase
      cl17173
      Location:169427
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      69612016..69635780
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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