Format

Send to:

Choose Destination
    • Showing Current items.

    Nelfe negative elongation factor complex member E, Rdbp [ Mus musculus (house mouse) ]

    Gene ID: 27632, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nelfeprovided by MGI
    Official Full Name
    negative elongation factor complex member E, Rdbpprovided by MGI
    Primary source
    MGI:MGI:102744
    See related
    Ensembl:ENSMUSG00000024369
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RD; NELF; Rdbp; NELF-E; D17H6S45
    Expression
    Ubiquitous expression in testis adult (RPKM 47.2), CNS E11.5 (RPKM 20.2) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nelfe in Genome Data Viewer
    Location:
    17 B1; 17 18.4 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (35069367..35075348)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (34850391..34856372)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (34987336..34993317)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene superkiller viralicidic activity 2-like (S. cerevisiae) Neighboring gene microRNA 6971 Neighboring gene microRNA 6970 Neighboring gene microRNA 6972 Neighboring gene complement factor B Neighboring gene complement component 2 (within H-2S)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of NELF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of NELF complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    negative elongation factor E
    Names
    RD RNA-binding protein
    RNA-binding protein RD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045863.1NP_001039328.1  negative elongation factor E

      See identical proteins and their annotated locations for NP_001039328.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI325150, AK147011, CX203833
      Consensus CDS
      CCDS28662.1
      UniProtKB/Swiss-Prot
      P19426
      UniProtKB/TrEMBL
      Q3UIA1
      Related
      ENSMUSP00000134272.2, ENSMUST00000173357.8
      Conserved Domains (1) summary
      cd12305
      Location:254328
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins
    2. NM_001045864.1NP_001039329.1  negative elongation factor E

      See identical proteins and their annotated locations for NP_001039329.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has an alternate splice site in the 5' UTR, compared to variant 1. Variants 1 and 3 encode the same protein.
      Source sequence(s)
      AI325150, CN525174, CT025759, DV662511
      Consensus CDS
      CCDS28662.1
      UniProtKB/Swiss-Prot
      P19426
      UniProtKB/TrEMBL
      Q3UIA1
      Related
      ENSMUSP00000094956.5, ENSMUST00000097343.11
      Conserved Domains (1) summary
      cd12305
      Location:254328
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins
    3. NM_138580.2NP_613046.2  negative elongation factor E

      See identical proteins and their annotated locations for NP_613046.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript. All variants encode the same protein.
      Source sequence(s)
      AI325150, AK131947, CX203833
      Consensus CDS
      CCDS28662.1
      UniProtKB/Swiss-Prot
      P19426
      UniProtKB/TrEMBL
      Q3UIA1
      Related
      ENSMUSP00000131195.3, ENSMUST00000165953.3
      Conserved Domains (1) summary
      cd12305
      Location:254328
      RRM_NELFE; RNA recognition motif in negative elongation factor E (NELF-E) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      35069367..35075348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center