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    Yme1l1 YME1-like 1 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 27377, updated on 6-Sep-2021

    Summary

    Official Symbol
    Yme1l1provided by MGI
    Official Full Name
    YME1-like 1 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1351651
    See related
    Ensembl:ENSMUSG00000026775
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fts; Ftsh; FtsH1
    Expression
    Broad expression in placenta adult (RPKM 18.6), CNS E11.5 (RPKM 15.0) and 21 other tissues See more
    Orthologs
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    Genomic context

    See Yme1l1 in Genome Data Viewer
    Location:
    2; 2 A3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (23046517..23089272)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (23155442..23199260)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (23012066..23054156)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene acyl-Coenzyme A binding domain containing 5 Neighboring gene microtubule associated serine/threonine kinase-like Neighboring gene nucleophosmin 1 pseudogene Neighboring gene POTE ankyrin domain family, member G like Neighboring gene predicted gene 13422

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP-dependent peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ATP-dependent peptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables ATP-dependent peptidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ATP-dependent zinc metalloprotease YME1L1
    Names
    ATP-dependent metalloprotease FtsH1
    YME1-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013771.5NP_038799.1  ATP-dependent zinc metalloprotease YME1L1

      See identical proteins and their annotated locations for NP_038799.1

      Status: VALIDATED

      Source sequence(s)
      AF090430, AL928706, BB624412
      Consensus CDS
      CCDS15728.1
      UniProtKB/Swiss-Prot
      O88967
      Related
      ENSMUSP00000028117.4, ENSMUST00000028117.4
      Conserved Domains (4) summary
      TIGR01241
      Location:275708
      FtsH_fam; ATP-dependent metalloprotease FtsH
      pfam00004
      Location:317448
      AAA; ATPase family associated with various cellular activities (AAA)
      pfam01434
      Location:528706
      Peptidase_M41; Peptidase family M41
      cl21455
      Location:273337
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      23046517..23089272
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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