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    Bcap31 B cell receptor associated protein 31 [ Mus musculus (house mouse) ]

    Gene ID: 27061, updated on 31-Jan-2019

    Summary

    Official Symbol
    Bcap31provided by MGI
    Official Full Name
    B cell receptor associated protein 31provided by MGI
    Primary source
    MGI:MGI:1350933
    See related
    Ensembl:ENSMUSG00000002015
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bap31
    Expression
    Ubiquitous expression in placenta adult (RPKM 68.6), subcutaneous fat pad adult (RPKM 42.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Bcap31 in Genome Data Viewer
    Location:
    X; X A7.3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (73686178..73717815, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (70931522..70961514, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32261 Neighboring gene solute carrier family 6 (neurotransmitter transporter, creatine), member 8 Neighboring gene ATP-binding cassette, sub-family D (ALD), member 1 Neighboring gene plexin B3 Neighboring gene serine/arginine-rich protein specific kinase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    MHC class I protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    ER to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ER to Golgi vesicle-mediated transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    ER to Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    calcium-mediated signaling using intracellular calcium source ISO
    Inferred from Sequence Orthology
    more info
     
    immune response IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of endoplasmic reticulum calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ER-associated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mitochondrial calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of retrograde protein transport, ER to cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein localization to endoplasmic reticulum exit site IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    spermatogenesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi cisterna membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with Sec61 translocon complex ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    lipid droplet ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    perinuclear endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    B-cell receptor-associated protein 31
    Names
    BCR-associated protein 31
    accessory protein BAP31
    p28

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001313698.1NP_001300627.1  B-cell receptor-associated protein 31

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AI838720, AK011500, AL805924, CX226458
      Consensus CDS
      CCDS30209.1
      UniProtKB/Swiss-Prot
      Q61335
      Conserved Domains (1) summary
      pfam05529
      Location:1223
      Bap31; B-cell receptor-associated protein 31-like
    2. NM_012060.5NP_036190.2  B-cell receptor-associated protein 31

      See identical proteins and their annotated locations for NP_036190.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AI838720, AK011500, AL805924, CB954946
      Consensus CDS
      CCDS30209.1
      UniProtKB/Swiss-Prot
      Q61335
      Related
      ENSMUSP00000002091.5, ENSMUST00000002091.5
      Conserved Domains (1) summary
      pfam05529
      Location:1223
      Bap31; B-cell receptor-associated protein 31-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      73686178..73717815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247600.2XP_011245902.1  B-cell receptor-associated protein 31 isoform X1

      See identical proteins and their annotated locations for XP_011245902.1

      UniProtKB/Swiss-Prot
      Q61335
      Conserved Domains (1) summary
      pfam05529
      Location:1223
      Bap31; B-cell receptor-associated protein 31-like
    2. XM_006528048.2XP_006528111.1  B-cell receptor-associated protein 31 isoform X1

      See identical proteins and their annotated locations for XP_006528111.1

      UniProtKB/Swiss-Prot
      Q61335
      Conserved Domains (1) summary
      pfam05529
      Location:1223
      Bap31; B-cell receptor-associated protein 31-like
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