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    Sh3d19 SH3 domain protein D19 [ Mus musculus (house mouse) ]

    Gene ID: 27059, updated on 5-Aug-2018

    Summary

    Official Symbol
    Sh3d19provided by MGI
    Official Full Name
    SH3 domain protein D19provided by MGI
    Primary source
    MGI:MGI:1350923
    See related
    Ensembl:ENSMUSG00000028082 Vega:OTTMUSG00000044337
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kryn; AW011754
    Expression
    Ubiquitous expression in bladder adult (RPKM 21.0), colon adult (RPKM 8.2) and 25 other tissues See more
    Orthologs

    Genomic context

    See Sh3d19 in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (85970953..86130522)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (85888356..85934444)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene glycosyltransferase 28 domain containing 2 Neighboring gene predicted gene 9790 Neighboring gene protease, serine 48 Neighboring gene small nucleolar RNA, C/D box U73A Neighboring gene ribosomal protein S3A1 Neighboring gene U73B small nuclear RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    proline-rich region binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of membrane protein ectodomain proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SH3 domain-containing protein 19
    Names
    SH3 domain containing protein D 19

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082414.2NP_001075883.2  SH3 domain-containing protein 19

      See identical proteins and their annotated locations for NP_001075883.2

      Status: VALIDATED

      Source sequence(s)
      AC133508
      Consensus CDS
      CCDS38469.2
      UniProtKB/Swiss-Prot
      Q91X43
      Related
      ENSMUSP00000103291.2, ENSMUST00000107664.2
      Conserved Domains (3) summary
      cd11814
      Location:418467
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:574624
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:498549
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      85970953..86130522
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319605.1XP_017175094.1  SH3 domain-containing protein 19 isoform X6

    2. XM_006501549.3XP_006501612.2  SH3 domain-containing protein 19 isoform X4

      Conserved Domains (1) summary
      cl17036
      Location:694743
      SH3; Src Homology 3 domain superfamily
    3. XM_006501546.3XP_006501609.2  SH3 domain-containing protein 19 isoform X1

      Conserved Domains (3) summary
      cd11814
      Location:694743
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:850900
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:774825
      SH3; Src Homology 3 domain superfamily
    4. XM_011240136.2XP_011238438.1  SH3 domain-containing protein 19 isoform X5

      See identical proteins and their annotated locations for XP_011238438.1

      Related
      ENSMUSP00000138320.1, OTTMUSP00000065049, ENSMUST00000182666.7, OTTMUST00000116683
      Conserved Domains (3) summary
      cd11814
      Location:419468
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:575625
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:499550
      SH3; Src Homology 3 domain superfamily
    5. XM_011240135.2XP_011238437.1  SH3 domain-containing protein 19 isoform X2

      Conserved Domains (3) summary
      cd11814
      Location:700749
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:856906
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:780831
      SH3; Src Homology 3 domain superfamily
    6. XM_006501547.3XP_006501610.1  SH3 domain-containing protein 19 isoform X3

      See identical proteins and their annotated locations for XP_006501610.1

      Conserved Domains (3) summary
      cd11814
      Location:635684
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:791841
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:715766
      SH3; Src Homology 3 domain superfamily
    7. XM_006501550.3XP_006501613.1  SH3 domain-containing protein 19 isoform X5

      See identical proteins and their annotated locations for XP_006501613.1

      Conserved Domains (3) summary
      cd11814
      Location:419468
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:575625
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:499550
      SH3; Src Homology 3 domain superfamily
    8. XM_006501548.3XP_006501611.1  SH3 domain-containing protein 19 isoform X3

      See identical proteins and their annotated locations for XP_006501611.1

      Conserved Domains (3) summary
      cd11814
      Location:635684
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:791841
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      cl17036
      Location:715766
      SH3; Src Homology 3 domain superfamily

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_012059.2: Suppressed sequence

      Description
      NM_012059.2: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: SH3D19 (GeneID:152503).
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