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    Sh3d19 SH3 domain protein D19 [ Mus musculus (house mouse) ]

    Gene ID: 27059, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sh3d19provided by MGI
    Official Full Name
    SH3 domain protein D19provided by MGI
    Primary source
    MGI:MGI:1350923
    See related
    Ensembl:ENSMUSG00000028082
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kr; Kryn; AW011754
    Expression
    Ubiquitous expression in bladder adult (RPKM 21.0), colon adult (RPKM 8.2) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Sh3d19 in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (85878112..86037833)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (85970805..86130526)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (85888356..85934444)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene 9790 Neighboring gene predicted gene, 27811 Neighboring gene protease, serine 48 Neighboring gene predicted gene, 25188 Neighboring gene small nucleolar RNA, C/D box U73A Neighboring gene small nucleolar RNA, C/D box U73B Neighboring gene ribosomal protein S3A1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables proline-rich region binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of membrane protein ectodomain proteolysis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SH3 domain-containing protein 19
    Names
    SH3 domain containing protein D 19

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082414.3NP_001075883.3  SH3 domain-containing protein 19

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC133508, AC138528
      Consensus CDS
      CCDS38469.2
      Related
      ENSMUSP00000158832.2, ENSMUST00000238545.2
      Conserved Domains (4) summary
      cd11814
      Location:635684
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:791841
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:38559
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:715766
      SH3; Src Homology 3 domain superfamily
    2. NM_001374679.1NP_001361608.1  SH3 domain-containing protein 19

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC133508, AC138528
      Consensus CDS
      CCDS89646.1
      Conserved Domains (4) summary
      cd11814
      Location:635684
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:791841
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:38559
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:715766
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      85878112..86037833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501546.5XP_006501609.3  SH3 domain-containing protein 19 isoform X1

      Related
      ENSMUSP00000158699.2, ENSMUST00000238443.2
      Conserved Domains (5) summary
      PTZ00449
      Location:245705
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd11814
      Location:840889
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:9961046
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:50375
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:920971
      SH3; Src Homology 3 domain superfamily
    2. XM_017319605.3XP_017175094.2  SH3 domain-containing protein 19 isoform X5

      Conserved Domains (2) summary
      PTZ00449
      Location:245666
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      PHA03247
      Location:50375
      PHA03247; large tegument protein UL36; Provisional
    3. XM_011240136.4XP_011238438.1  SH3 domain-containing protein 19 isoform X4

      See identical proteins and their annotated locations for XP_011238438.1

      Related
      ENSMUSP00000138320.2, ENSMUST00000182666.8
      Conserved Domains (4) summary
      cd11814
      Location:419468
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:575625
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:25305
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:499550
      SH3; Src Homology 3 domain superfamily
    4. XM_011240135.4XP_011238437.1  SH3 domain-containing protein 19 isoform X2

      Conserved Domains (4) summary
      cd11814
      Location:700749
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:856906
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:103624
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:780831
      SH3; Src Homology 3 domain superfamily
    5. XM_006501547.4XP_006501610.1  SH3 domain-containing protein 19 isoform X3

      See identical proteins and their annotated locations for XP_006501610.1

      Conserved Domains (4) summary
      cd11814
      Location:635684
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:791841
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:38559
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:715766
      SH3; Src Homology 3 domain superfamily
    6. XM_006501550.5XP_006501613.1  SH3 domain-containing protein 19 isoform X4

      See identical proteins and their annotated locations for XP_006501613.1

      Related
      ENSMUSP00000158600.2, ENSMUST00000238331.2
      Conserved Domains (4) summary
      cd11814
      Location:419468
      SH3_Eve1_1; First Src homology 3 domain of ADAM-binding protein Eve-1
      cd11816
      Location:575625
      SH3_Eve1_3; Third Src homology 3 domain of ADAM-binding protein Eve-1
      PHA03247
      Location:25305
      PHA03247; large tegument protein UL36; Provisional
      cl17036
      Location:499550
      SH3; Src Homology 3 domain superfamily

    RNA

    1. XR_003954328.2 RNA Sequence

    2. XR_004941332.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_012059.2: Suppressed sequence

      Description
      NM_012059.2: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: SH3D19 (GeneID:152503).
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