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    Myo9a myosin IXa [ Mus musculus (house mouse) ]

    Gene ID: 270163, updated on 12-Aug-2018

    Summary

    Official Symbol
    Myo9aprovided by MGI
    Official Full Name
    myosin IXaprovided by MGI
    Primary source
    MGI:MGI:107735
    See related
    Ensembl:ENSMUSG00000039585 Vega:OTTMUSG00000034123
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C230003M11; 4732465J09Rik; C130068I12Rik
    Expression
    Broad expression in CNS E18 (RPKM 7.1), whole brain E14.5 (RPKM 5.5) and 21 other tissues See more
    Orthologs

    Genomic context

    See Myo9a in Genome Data Viewer
    Location:
    9 B; 9 32.13 cM
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (59750843..59928866)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (59598981..59776673)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene GRAM domain containing 2 Neighboring gene predicted gene, 39347 Neighboring gene SUMO/sentrin specific peptidase 8 Neighboring gene predicted gene 7613 Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene predicted gene, 20275 Neighboring gene predicted gene 7616 Neighboring gene nuclear receptor subfamily 2, group E, member 3 Neighboring gene thrombospondin, type I, domain containing 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    establishment of epithelial cell apical/basal polarity ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    myosin complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    unconventional myosin-IXa
    Names
    unconventional myosin-9a

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173018.2NP_766606.2  unconventional myosin-IXa

      Status: VALIDATED

      Source sequence(s)
      AC131749, AC156795, AC160637
      Consensus CDS
      CCDS52820.1
      UniProtKB/TrEMBL
      D3Z3A8
      Related
      ENSMUSP00000122852.1, OTTMUSP00000046733, ENSMUST00000136740.7, OTTMUST00000086327
      Conserved Domains (6) summary
      smart00015
      Location:11161137
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431015
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20732121
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21342319
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601005
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      59750843..59928866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511209.3XP_006511272.1  unconventional myosin-IXa isoform X1

      See identical proteins and their annotated locations for XP_006511272.1

      Conserved Domains (6) summary
      smart00015
      Location:11171138
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431016
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20752123
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21362321
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601006
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    2. XM_006511208.2XP_006511271.1  unconventional myosin-IXa isoform X1

      See identical proteins and their annotated locations for XP_006511271.1

      Conserved Domains (6) summary
      smart00015
      Location:11171138
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431016
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20752123
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21362321
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601006
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    3. XM_006511212.2XP_006511275.1  unconventional myosin-IXa isoform X4

      Related
      ENSMUSP00000117432.1, OTTMUSP00000046734, ENSMUST00000135298.7, OTTMUST00000086328
      Conserved Domains (6) summary
      smart00015
      Location:11171138
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431016
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20752123
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21362321
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601006
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    4. XM_006511211.2XP_006511274.1  unconventional myosin-IXa isoform X3

      Conserved Domains (6) summary
      smart00015
      Location:11171138
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431016
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20742122
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21352320
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601006
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    5. XM_006511216.2XP_006511279.1  unconventional myosin-IXa isoform X7

      Conserved Domains (6) summary
      smart00015
      Location:11171138
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431016
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20032051
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:20642249
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601006
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    6. XM_006511217.2XP_006511280.1  unconventional myosin-IXa isoform X9

      Conserved Domains (6) summary
      smart00015
      Location:11171138
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431016
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20032051
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:20642249
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601006
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    7. XM_006511210.2XP_006511273.1  unconventional myosin-IXa isoform X2

      Conserved Domains (6) summary
      smart00015
      Location:11161137
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431015
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20742122
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21352320
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601005
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    8. XM_017313399.1XP_017168888.1  unconventional myosin-IXa isoform X8

    9. XM_006511220.2XP_006511283.1  unconventional myosin-IXa isoform X11

      See identical proteins and their annotated locations for XP_006511283.1

      UniProtKB/Swiss-Prot
      Q8C170
      Related
      ENSMUSP00000119401.1, OTTMUSP00000046735, ENSMUST00000128341.1, OTTMUST00000086329
      Conserved Domains (6) summary
      smart00015
      Location:11161137
      IQ; Calmodulin-binding motif
      smart00242
      Location:1431015
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20022050
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:20632248
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:1601005
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    10. XM_006511213.2XP_006511276.1  unconventional myosin-IXa isoform X5

      Conserved Domains (6) summary
      smart00015
      Location:10981119
      IQ; Calmodulin-binding motif
      smart00242
      Location:143997
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20562104
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21172302
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:160987
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    11. XM_006511215.2XP_006511278.1  unconventional myosin-IXa isoform X6

      Conserved Domains (6) summary
      smart00015
      Location:10971118
      IQ; Calmodulin-binding motif
      smart00242
      Location:143996
      MYSc; Myosin. Large ATPases
      cd00029
      Location:20552103
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd04377
      Location:21162301
      RhoGAP_myosin_IX; RhoGAP_myosin_IX: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in class IX myosins. Class IX myosins contain a characteristic head domain, a neck domain, a tail domain which contains a C6H2-zinc binding motif and a ...
      cd01385
      Location:160986
      MYSc_Myo9; class IX myosin, motor domain
      cl00155
      Location:6110
      UBQ; Ubiquitin-like proteins
    12. XM_017313400.1XP_017168889.1  unconventional myosin-IXa isoform X10

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