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    Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma [ Mus musculus (house mouse) ]

    Gene ID: 26931, updated on 9-Sep-2018

    Summary

    Official Symbol
    Ppp2r5cprovided by MGI
    Official Full Name
    protein phosphatase 2, regulatory subunit B', gammaprovided by MGI
    Primary source
    MGI:MGI:1349475
    See related
    Ensembl:ENSMUSG00000017843
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C85228; AI060890; AW545884; D12Bwg0916e; 2610043M05Rik; 2700063L20Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 41.8), cortex adult (RPKM 18.2) and 27 other tissues See more
    Orthologs

    Genomic context

    See Ppp2r5c in Genome Data Viewer
    Location:
    12 F1; 12 60.56 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (110447179..110583075)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (111685389..111821271)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene predicted gene 9063 Neighboring gene predicted gene, 40577 Neighboring gene uncharacterized LOC102638940 Neighboring gene RIKEN cDNA B930059L03 gene Neighboring gene predicted gene, 35558

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA0044

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    proteasome-mediated ubiquitin-dependent protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    contributes_to protein dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of protein autophosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus TAS
    Traceable Author Statement
    more info
    PubMed 
    protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
    Names
    B56/PP2A gamma
    Band 8A
    PP2A B subunit isoform B'-alpha-3
    PP2A B subunit isoform B'-gamma
    PP2A B subunit isoform B56-gamma
    PP2A B subunit isoform PR61-gamma
    PP2A B subunit isoform R5-gamma
    protein phosphatase 2, regulatory subunit B (B56), gamma isoform

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081457.3NP_001074926.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform b

      See identical proteins and their annotated locations for NP_001074926.1

      Status: VALIDATED

      Source sequence(s)
      AC152827, AK031584, CV558022
      Consensus CDS
      CCDS36558.1
      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000105458.1, ENSMUST00000109832.2
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    2. NM_001081458.3NP_001074927.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform c

      See identical proteins and their annotated locations for NP_001074927.1

      Status: VALIDATED

      Source sequence(s)
      AK031584, BQ175856, CV558022
      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000152865.1, ENSMUST00000221715.1
      Conserved Domains (2) summary
      PLN00122
      Location:342443
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:34437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    3. NM_001135001.2NP_001128473.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform d

      Status: VALIDATED

      Source sequence(s)
      AK031584, AK129042, CJ312853, CX217314
      UniProtKB/TrEMBL
      Q6ZQK4
      Conserved Domains (2) summary
      PLN00122
      Location:399500
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    4. NM_001364204.1NP_001351133.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform e

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:89494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    5. NM_001364205.1NP_001351134.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform f

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    6. NM_001364206.1NP_001351135.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform h

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    7. NM_001364207.1NP_001351136.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform i

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    8. NM_001364208.1NP_001351137.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform j

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    9. NM_001364209.1NP_001351138.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform k

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    10. NM_001364210.1NP_001351139.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform l

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    11. NM_001364211.1NP_001351140.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform m

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    12. NM_001364212.1NP_001351141.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform n

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:19357
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    13. NM_001364213.1NP_001351142.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform o

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:1305
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    14. NM_001364214.1NP_001351143.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform g

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    15. NM_012023.4NP_036153.2  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform a

      See identical proteins and their annotated locations for NP_036153.2

      Status: VALIDATED

      Source sequence(s)
      AC152827, AK031584, CV558022, CX568604
      Consensus CDS
      CCDS36557.1
      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000082053.3, ENSMUST00000084985.10
      Conserved Domains (2) summary
      PLN00122
      Location:342442
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:34437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      110447179..110583075
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515924.2XP_006515987.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1

      Conserved Domains (2) summary
      PLN00122
      Location:399499
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    2. XM_006515918.2XP_006515981.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X3

      Conserved Domains (2) summary
      PLN00122
      Location:399499
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    3. XM_006515919.2XP_006515982.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X4

      Conserved Domains (1) summary
      pfam01603
      Location:89494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    4. XM_006515917.1XP_006515980.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X2

      Conserved Domains (2) summary
      PLN00122
      Location:399499
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    5. XM_006515923.3XP_006515986.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X9

      Conserved Domains (2) summary
      PLN00122
      Location:399499
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    6. XM_006515922.2XP_006515985.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X7

      Conserved Domains (2) summary
      PLN00122
      Location:399501
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    7. XM_006515921.1XP_006515984.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X6

      Conserved Domains (2) summary
      PLN00122
      Location:342442
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    8. XM_006515920.1XP_006515983.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X5

      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    9. XM_017315081.1XP_017170570.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X8

      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    10. XM_017315082.1XP_017170571.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X10

      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000152282.1, ENSMUST00000221074.1
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    11. XM_017315084.1XP_017170573.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X12

      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    12. XM_017315083.1XP_017170572.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X11

      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    13. XM_017315085.1XP_017170574.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X13

      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    14. XM_017315086.1XP_017170575.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X14

      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037934.1: Suppressed sequence

      Description
      NM_001037934.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
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