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    Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma [ Mus musculus (house mouse) ]

    Gene ID: 26931, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ppp2r5cprovided by MGI
    Official Full Name
    protein phosphatase 2, regulatory subunit B', gammaprovided by MGI
    Primary source
    MGI:MGI:1349475
    See related
    Ensembl:ENSMUSG00000017843
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C85228; AI060890; AW545884; D12Bwg0916e; 2610043M05Rik; 2700063L20Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 41.8), cortex adult (RPKM 18.2) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ppp2r5c in Genome Data Viewer
    Location:
    12 F1; 12 60.56 cM
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (110413532..110549509)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (110447144..110583075)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (111685389..111821271)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene 9063 Neighboring gene predicted gene, 40577 Neighboring gene predicted gene, 19605 Neighboring gene RIKEN cDNA B930059L03 gene Neighboring gene predicted gene, 35558 Neighboring gene dynein cytoplasmic 1 heavy chain 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA0044

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein phosphatase regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus TAS
    Traceable Author Statement
    more info
    PubMed 
    part_of protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of protein phosphatase type 2A complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
    Names
    B56/PP2A gamma
    Band 8A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081457.3NP_001074926.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform b

      See identical proteins and their annotated locations for NP_001074926.1

      Status: VALIDATED

      Source sequence(s)
      AC152827, AK031584, CV558022
      Consensus CDS
      CCDS36558.1
      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000105458.2, ENSMUST00000109832.3
      Conserved Domains (1) summary
      pfam01603
      Location:34437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    2. NM_001081458.3NP_001074927.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform c

      See identical proteins and their annotated locations for NP_001074927.1

      Status: VALIDATED

      Source sequence(s)
      AK031584, BQ175856, CV558022
      Consensus CDS
      CCDS88404.1
      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000152865.2, ENSMUST00000221715.2
      Conserved Domains (2) summary
      PLN00122
      Location:342443
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:34437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    3. NM_001135001.2NP_001128473.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform d

      Status: VALIDATED

      Source sequence(s)
      AK031584, AK129042, CJ312853, CX217314
      UniProtKB/TrEMBL
      Q6ZQK4
      Conserved Domains (2) summary
      PLN00122
      Location:399500
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    4. NM_001364204.1NP_001351133.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform e

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:89494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    5. NM_001364205.1NP_001351134.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform f

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    6. NM_001364206.1NP_001351135.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform h

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Consensus CDS
      CCDS88403.1
      Related
      ENSMUSP00000152282.2, ENSMUST00000221074.2
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    7. NM_001364207.1NP_001351136.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform i

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    8. NM_001364208.1NP_001351137.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform j

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    9. NM_001364209.1NP_001351138.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform k

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    10. NM_001364210.1NP_001351139.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform l

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    11. NM_001364211.1NP_001351140.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform m

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32380
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    12. NM_001364212.1NP_001351141.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform n

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:19357
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    13. NM_001364213.1NP_001351142.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform o

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:1305
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    14. NM_001364214.1NP_001351143.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform g

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:32437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    15. NM_001373949.1NP_001360878.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform p

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    16. NM_001373950.1NP_001360879.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform q

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    17. NM_001373951.1NP_001360880.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform r

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:91474
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    18. NM_001373952.1NP_001360881.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform s

      Status: VALIDATED

      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:2335
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    19. NM_001373953.1NP_001360882.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform t

      Status: VALIDATED

      Description
      Transcript Variant: This variant (20), as well as variant 21, encodes isoform t.
      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:1362
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    20. NM_001373954.1NP_001360883.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform t

      Status: VALIDATED

      Description
      Transcript Variant: This variant (21), as well as variant 20, encodes isoform t.
      Source sequence(s)
      AC152827, AL591582
      Conserved Domains (1) summary
      pfam01603
      Location:1362
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    21. NM_012023.4NP_036153.2  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform a

      See identical proteins and their annotated locations for NP_036153.2

      Status: VALIDATED

      Source sequence(s)
      AC152827, AK031584, CV558022, CX568604
      Consensus CDS
      CCDS36557.1
      UniProtKB/Swiss-Prot
      Q60996
      Related
      ENSMUSP00000082053.4, ENSMUST00000084985.11
      Conserved Domains (2) summary
      PLN00122
      Location:342442
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:34437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    RNA

    1. NR_164198.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL591582

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      110413532..110549509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515924.4XP_006515987.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1

      Conserved Domains (1) summary
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    2. XM_006515918.4XP_006515981.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X2

      Conserved Domains (1) summary
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    3. XM_006515923.5XP_006515986.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X4

      Conserved Domains (1) summary
      pfam01603
      Location:91494
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    4. XM_006515921.3XP_006515984.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X3

      Conserved Domains (1) summary
      pfam01603
      Location:91437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    5. XM_030246738.2XP_030102598.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X5

      Conserved Domains (1) summary
      pfam01603
      Location:91437
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    6. XM_030246740.1XP_030102600.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X6

      Conserved Domains (1) summary
      pfam01603
      Location:1362
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001037934.1: Suppressed sequence

      Description
      NM_001037934.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
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