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    Eif2s3x eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked [ Mus musculus (house mouse) ]

    Gene ID: 26905, updated on 5-Sep-2021

    Summary

    Official Symbol
    Eif2s3xprovided by MGI
    Official Full Name
    eukaryotic translation initiation factor 2, subunit 3, structural gene X-linkedprovided by MGI
    Primary source
    MGI:MGI:1349431
    See related
    Ensembl:ENSMUSG00000035150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Eif-2g; Eif-2gx; AA409828; AA547477; AI314668; eIF-2-gamma X
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 48.5), placenta adult (RPKM 48.0) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Eif2s3x in Genome Data Viewer
    Location:
    X C3; X 41.52 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (93232315..93256257, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (94188709..94212651, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (91434048..91457990, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted pseudogene 6987 Neighboring gene zinc finger protein X-linked Neighboring gene predicted gene, 46691 Neighboring gene kelch-like 15 Neighboring gene microRNA 7673 Neighboring gene predicted gene 5400

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to tRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation factor activity, RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation initiation factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in formation of translation preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of translational fidelity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of eukaryotic translation initiation factor 2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of eukaryotic translation initiation factor 2 complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 2 subunit 3, X-linked
    Names
    eukaryotic translation initiation factor 2 subunit gamma, X-linked
    NP_036140.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012010.3NP_036140.1  eukaryotic translation initiation factor 2 subunit 3, X-linked

      See identical proteins and their annotated locations for NP_036140.1

      Status: VALIDATED

      Source sequence(s)
      AL646049, AL646092
      Consensus CDS
      CCDS30277.1
      UniProtKB/Swiss-Prot
      Q9Z0N1
      UniProtKB/TrEMBL
      Q3TML6
      Related
      ENSMUSP00000059395.9, ENSMUST00000050328.15
      Conserved Domains (1) summary
      PTZ00327
      Location:13466
      PTZ00327; eukaryotic translation initiation factor 2 gamma subunit; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      93232315..93256257 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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