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    Sap130 Sin3A associated protein [ Mus musculus (house mouse) ]

    Gene ID: 269003, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sap130provided by MGI
    Official Full Name
    Sin3A associated proteinprovided by MGI
    Primary source
    MGI:MGI:1919782
    See related
    Ensembl:ENSMUSG00000024260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6720406D06; 2610304F09Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 32.4), thymus adult (RPKM 15.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sap130 in Genome Data Viewer
    Location:
    18; 18 B1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (31767421..31856121)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (31634368..31723068)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (31794037..31882715)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38606 Neighboring gene solute carrier family 25, member 46 Neighboring gene predicted gene, 52327 Neighboring gene protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) pseudogene Neighboring gene AMME chromosomal region gene 1-like Neighboring gene predicted gene, 26533

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Sin3-type complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    histone deacetylase complex subunit SAP130
    Names
    130 kDa Sin3-associated polypeptide
    Sin3A associated protein, 130kDa
    sin3-associated polypeptide p130
    NP_001344483.1
    NP_001344484.1
    NP_766553.1
    XP_006526012.1
    XP_006526014.1
    XP_006526015.1
    XP_006526016.1
    XP_030106331.1
    XP_036017054.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357554.1NP_001344483.1  histone deacetylase complex subunit SAP130 isoform 2

      Status: VALIDATED

      Source sequence(s)
      BC066030, BQ032928, BY281875
      Consensus CDS
      CCDS89207.1
      Related
      ENSMUSP00000157127.2, ENSMUST00000235017.2
      Conserved Domains (2) summary
      PHA03247
      Location:98492
      PHA03247; large tegument protein UL36; Provisional
      pfam16014
      Location:6351040
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
    2. NM_001357555.1NP_001344484.1  histone deacetylase complex subunit SAP130 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC156981, AC161511, BQ032928
      Conserved Domains (4) summary
      PHA02732
      Location:257486
      PHA02732; hypothetical protein; Provisional
      pfam15254
      Location:539666
      CCDC14; Coiled-coil domain-containing protein 14
      pfam16014
      Location:6541059
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
      cl26464
      Location:8359
      Atrophin-1; Atrophin-1 family
    3. NM_172965.3NP_766553.1  histone deacetylase complex subunit SAP130 isoform 1

      See identical proteins and their annotated locations for NP_766553.1

      Status: VALIDATED

      Source sequence(s)
      AK053675, BQ032928, BY281875
      Consensus CDS
      CCDS57117.1
      UniProtKB/Swiss-Prot
      Q8BIH0
      UniProtKB/TrEMBL
      A0A0R4J060
      Related
      ENSMUSP00000025109.8, ENSMUST00000025109.8
      Conserved Domains (1) summary
      pfam16014
      Location:6341039
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      31767421..31856121
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525951.4XP_006526014.1  histone deacetylase complex subunit SAP130 isoform X2

      See identical proteins and their annotated locations for XP_006526014.1

      UniProtKB/Swiss-Prot
      Q8BIH0
      Conserved Domains (2) summary
      PHA03247
      Location:98492
      PHA03247; large tegument protein UL36; Provisional
      pfam16014
      Location:6351040
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
    2. XM_006525949.3XP_006526012.1  histone deacetylase complex subunit SAP130 isoform X1

      Conserved Domains (3) summary
      PHA02732
      Location:257486
      PHA02732; hypothetical protein; Provisional
      PHA03247
      Location:8359
      PHA03247; large tegument protein UL36; Provisional
      pfam16014
      Location:6551060
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
    3. XM_006525953.3XP_006526016.1  histone deacetylase complex subunit SAP130 isoform X3

      Conserved Domains (2) summary
      PHA03247
      Location:437871
      PHA03247; large tegument protein UL36; Provisional
      pfam16014
      Location:6551025
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
    4. XM_030250471.2XP_030106331.1  histone deacetylase complex subunit SAP130 isoform X4

      Conserved Domains (4) summary
      PHA02732
      Location:257486
      PHA02732; hypothetical protein; Provisional
      PHA03247
      Location:8359
      PHA03247; large tegument protein UL36; Provisional
      PRK14971
      Location:581706
      PRK14971; DNA polymerase III subunit gamma/tau
      pfam16014
      Location:6541024
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
    5. XM_006525952.5XP_006526015.1  histone deacetylase complex subunit SAP130 isoform X2

      See identical proteins and their annotated locations for XP_006526015.1

      UniProtKB/Swiss-Prot
      Q8BIH0
      Conserved Domains (2) summary
      PHA03247
      Location:98492
      PHA03247; large tegument protein UL36; Provisional
      pfam16014
      Location:6351040
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
    6. XM_036161161.1XP_036017054.1  histone deacetylase complex subunit SAP130 isoform X5

      Conserved Domains (2) summary
      PHA03247
      Location:34471
      PHA03247; large tegument protein UL36; Provisional
      pfam16014
      Location:6141019
      SAP130_C; Histone deacetylase complex subunit SAP130 C-terminus
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