Format

Send to:

Choose Destination
    • Showing Current items.

    Med14 mediator complex subunit 14 [ Mus musculus (house mouse) ]

    Gene ID: 26896, updated on 2-Oct-2018

    Summary

    Official Symbol
    Med14provided by MGI
    Official Full Name
    mediator complex subunit 14provided by MGI
    Primary source
    MGI:MGI:1349442
    See related
    Ensembl:ENSMUSG00000064127 Vega:OTTMUSG00000016997
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ORF1; Crsp2; Gm641; Trap170; AU041628; 9930001L01Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 13.6), whole brain E14.5 (RPKM 7.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Med14 in Genome Data Viewer
    Location:
    X; X A1.1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (12675371..12762106, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (12252497..12339099, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene nucleolar protein 56 pseudogene Neighboring gene RIKEN cDNA 1810030O07 gene Neighboring gene predicted pseudogene 4984 Neighboring gene predicted gene 14634 Neighboring gene expressed sequence AA414768

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription coregulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mediator complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 14
    Names
    CRSP complex subunit 2
    cofactor required for Sp1 transcriptional activation subunit 2 (150 kDa)
    cofactor required for Sp1 transcriptional activation, subunit 2
    thyroid hormone receptor-associated protein complex 170 kDa component

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001048208.1NP_001041673.1  mediator of RNA polymerase II transcription subunit 14 isoform a

      See identical proteins and their annotated locations for NP_001041673.1

      Status: VALIDATED

      Source sequence(s)
      BC065072, BX000537, CN724751
      Consensus CDS
      CCDS40874.1
      UniProtKB/Swiss-Prot
      A2ABV5
      Related
      ENSMUSP00000094239.4, OTTMUSP00000018469, ENSMUST00000096495.10, OTTMUST00000041216
      Conserved Domains (2) summary
      pfam03957
      Location:10521147
      Jun; Jun-like transcription factor
      pfam08638
      Location:57244
      Med14; Mediator complex subunit MED14
    2. NM_012005.3NP_036135.3  mediator of RNA polymerase II transcription subunit 14 isoform b

      Status: VALIDATED

      Source sequence(s)
      BC065072, BX631997, CN724751
      UniProtKB/Swiss-Prot
      A2ABV5
      Conserved Domains (2) summary
      pfam03957
      Location:10521147
      Jun; Jun-like transcription factor
      pfam08638
      Location:57244
      Med14; Mediator complex subunit MED14

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      12675371..12762106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527629.3XP_006527692.1  mediator of RNA polymerase II transcription subunit 14 isoform X1

      Conserved Domains (2) summary
      pfam08430
      Location:10321133
      Forkhead_N; Forkhead N-terminal region
      pfam08638
      Location:57244
      Med14; Mediator complex subunit MED14
    2. XM_017318510.1XP_017173999.1  mediator of RNA polymerase II transcription subunit 14 isoform X3

    3. XM_017318511.1XP_017174000.1  mediator of RNA polymerase II transcription subunit 14 isoform X4

    4. XM_017318509.1XP_017173998.1  mediator of RNA polymerase II transcription subunit 14 isoform X2

    5. XM_006527630.3XP_006527693.1  mediator of RNA polymerase II transcription subunit 14 isoform X5

      Conserved Domains (1) summary
      pfam08638
      Location:57244
      Med14; Mediator complex subunit MED14

    RNA

    1. XR_878029.2 RNA Sequence

    Support Center