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    Wdr24 WD repeat domain 24 [ Mus musculus (house mouse) ]

    Gene ID: 268933, updated on 23-Jun-2021

    Summary

    Official Symbol
    Wdr24provided by MGI
    Official Full Name
    WD repeat domain 24provided by MGI
    Primary source
    MGI:MGI:2446285
    See related
    Ensembl:ENSMUSG00000025737
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BC037651
    Expression
    Ubiquitous expression in thymus adult (RPKM 26.9), ovary adult (RPKM 24.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Wdr24 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26042601..26047704)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25823627..25828730)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (25960572..25965675)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene meteorin, glial cell differentiation regulator Neighboring gene F-box and leucine-rich repeat protein 16 Neighboring gene jumonji domain containing 8 Neighboring gene microRNA 3082 Neighboring gene STIP1 homology and U-Box containing protein 1 Neighboring gene rhomboid like 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC47001

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to amino acid starvation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of TOR signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of autophagy ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of GATOR2 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosomal membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GATOR complex protein WDR24
    Names
    WD repeat-containing protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173741.3NP_776102.1  GATOR complex protein WDR24

      See identical proteins and their annotated locations for NP_776102.1

      Status: VALIDATED

      Source sequence(s)
      AC159277
      Consensus CDS
      CCDS28531.1
      UniProtKB/Swiss-Prot
      Q8CFJ9
      Related
      ENSMUSP00000026833.6, ENSMUST00000026833.6
      Conserved Domains (4) summary
      COG2319
      Location:40323
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:75118
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:86323
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      cl24077
      Location:742787
      Zn_ribbon_17; Zinc-ribbon, C4HC2 type

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      26042601..26047704
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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