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    Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 [ Mus musculus (house mouse) ]

    Gene ID: 268930, updated on 5-Sep-2021

    Summary

    Official Symbol
    Pkmyt1provided by MGI
    Official Full Name
    protein kinase, membrane associated tyrosine/threonine 1provided by MGI
    Primary source
    MGI:MGI:2137630
    See related
    Ensembl:ENSMUSG00000023908
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Myt1; AW209059; 6230424P17
    Expression
    Ubiquitous expression in thymus adult (RPKM 44.6), testis adult (RPKM 32.4) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Pkmyt1 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (23945310..23955709)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (23726336..23736735)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (23863303..23873696)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene claudin 9 Neighboring gene RIKEN cDNA 1520401A03 gene Neighboring gene progestin and adipoQ receptor family member IV Neighboring gene kringle containing transmembrane protein 2 Neighboring gene RIKEN cDNA 9530082P21 gene Neighboring gene FLYWCH-type zinc finger 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
    Names
    MYT1 kinase
    NP_075545.2
    XP_006524373.1
    XP_006524374.1
    XP_030105682.1
    XP_030105683.1
    XP_030105685.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023058.3NP_075545.2  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

      See identical proteins and their annotated locations for NP_075545.2

      Status: PROVISIONAL

      Source sequence(s)
      AK158550
      Consensus CDS
      CCDS28460.1
      UniProtKB/Swiss-Prot
      Q9ESG9
      Related
      ENSMUSP00000024701.8, ENSMUST00000024701.9
      Conserved Domains (2) summary
      smart00220
      Location:101350
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14050
      Location:99348
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      23945310..23955709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249822.2XP_030105682.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X3

      Conserved Domains (1) summary
      cd14050
      Location:99348
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1
    2. XM_006524310.4XP_006524373.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1

      Conserved Domains (1) summary
      cd14050
      Location:148397
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1
    3. XM_030249825.2XP_030105685.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X5

      Conserved Domains (1) summary
      cl21453
      Location:61127
      PKc_like; Protein Kinases, catalytic domain
    4. XM_006524311.5XP_006524374.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X2

      Conserved Domains (1) summary
      cd14050
      Location:148397
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1
    5. XM_030249823.2XP_030105683.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X4

      Conserved Domains (1) summary
      cl21453
      Location:1216
      PKc_like; Protein Kinases, catalytic domain
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