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    Pkmyt1 protein kinase, membrane associated tyrosine/threonine 1 [ Mus musculus (house mouse) ]

    Gene ID: 268930, updated on 8-Oct-2018

    Summary

    Official Symbol
    Pkmyt1provided by MGI
    Official Full Name
    protein kinase, membrane associated tyrosine/threonine 1provided by MGI
    Primary source
    MGI:MGI:2137630
    See related
    Ensembl:ENSMUSG00000023908
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Myt1; AW209059; 6230424P17
    Expression
    Ubiquitous expression in thymus adult (RPKM 44.6), testis adult (RPKM 32.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See Pkmyt1 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (23726336..23736735)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (23863303..23873696)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene claudin 9 Neighboring gene RIKEN cDNA 1520401A03 gene Neighboring gene progestin and adipoQ receptor family member IV Neighboring gene kringle containing transmembrane protein 2 Neighboring gene RIKEN cDNA 9530082P21 gene Neighboring gene FLYWCH-type zinc finger 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
    Names
    MYT1 kinase
    NP_075545.2
    XP_006524373.1
    XP_006524374.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023058.3NP_075545.2  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

      See identical proteins and their annotated locations for NP_075545.2

      Status: PROVISIONAL

      Source sequence(s)
      AK158550
      Consensus CDS
      CCDS28460.1
      UniProtKB/Swiss-Prot
      Q9ESG9
      Related
      ENSMUSP00000024701.7, ENSMUST00000024701.8
      Conserved Domains (2) summary
      smart00220
      Location:101350
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14050
      Location:99348
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      23726336..23736735
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524311.3XP_006524374.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X2

      Conserved Domains (2) summary
      smart00220
      Location:150399
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14050
      Location:148397
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1
    2. XM_006524310.2XP_006524373.1  membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase isoform X1

      Conserved Domains (2) summary
      smart00220
      Location:150399
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14050
      Location:148397
      PKc_Myt1; Catalytic domain of the Dual-specificity protein kinase, Myt1
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