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    Cenph centromere protein H [ Mus musculus (house mouse) ]

    Gene ID: 26886, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cenphprovided by MGI
    Official Full Name
    centromere protein Hprovided by MGI
    Primary source
    MGI:MGI:1349448
    See related
    Ensembl:ENSMUSG00000045273
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ENP; CENP-H; AU044255; 1700021I11Rik; 2410018A12Rik; 2610042E16Rik; 2810046K12Rik
    Expression
    Biased expression in liver E14 (RPKM 15.8), CNS E11.5 (RPKM 12.8) and 9 other tissues See more
    Orthologs

    Genomic context

    See Cenph in Genome Data Viewer
    Location:
    13 53.23 cM; 13 D1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (100759686..100775899, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (101529641..101545854, complement)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 125 Neighboring gene cyclin-dependent kinase 7 Neighboring gene mitochondrial ribosomal protein S36 Neighboring gene cyclin B1 Neighboring gene solute carrier family 30 (zinc transporter), member 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    kinetochore binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    kinetochore binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    chromosome segregation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    kinetochore assembly IEA
    Inferred from Electronic Annotation
    more info
     
    kinetochore organization TAS
    Traceable Author Statement
    more info
    PubMed 
    mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    kinetochore IDA
    Inferred from Direct Assay
    more info
    PubMed 
    kinetochore ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    centromere protein H
    Names
    cenph
    centromere autoantigen H

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021886.2NP_068686.1  centromere protein H

      See identical proteins and their annotated locations for NP_068686.1

      Status: VALIDATED

      Source sequence(s)
      AC112701
      Consensus CDS
      CCDS26738.1
      UniProtKB/Swiss-Prot
      Q9QYM8
      Related
      ENSMUSP00000074988.3, ENSMUST00000075550.3
      Conserved Domains (1) summary
      pfam05837
      Location:134233
      CENP-H; Centromere protein H (CENP-H)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      100759686..100775899 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517678.3XP_006517741.1  centromere protein H isoform X1

      See identical proteins and their annotated locations for XP_006517741.1

      Conserved Domains (1) summary
      pfam05837
      Location:43142
      CENP-H; Centromere protein H (CENP-H)
    2. XM_006517676.3XP_006517739.1  centromere protein H isoform X1

      See identical proteins and their annotated locations for XP_006517739.1

      Conserved Domains (1) summary
      pfam05837
      Location:43142
      CENP-H; Centromere protein H (CENP-H)
    3. XM_011244667.2XP_011242969.1  centromere protein H isoform X1

      See identical proteins and their annotated locations for XP_011242969.1

      Conserved Domains (1) summary
      pfam05837
      Location:43142
      CENP-H; Centromere protein H (CENP-H)
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