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    Rab11fip4 RAB11 family interacting protein 4 (class II) [ Mus musculus (house mouse) ]

    Gene ID: 268451, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rab11fip4provided by MGI
    Official Full Name
    RAB11 family interacting protein 4 (class II)provided by MGI
    Primary source
    MGI:MGI:2442920
    See related
    Ensembl:ENSMUSG00000017639
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RAB11-; mKIAA1821; RAB11-FIP4; A730072L08Rik
    Expression
    Broad expression in cortex adult (RPKM 31.5), frontal lobe adult (RPKM 30.4) and 19 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rab11fip4 in Genome Data Viewer
    Location:
    11 B5; 11 46.88 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (79481847..79588842)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (79591021..79698016)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (79404714..79507514)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene neurofibromin 1 Neighboring gene ecotropic viral integration site 2b Neighboring gene ecotropic viral integration site 2 Neighboring gene ecotropic viral integration site 2a Neighboring gene RAB11 family interacting protein 4 (class II), opposite strand 1 Neighboring gene predicted gene, 23293 Neighboring gene predicted gene, 25867 Neighboring gene predicted gene, 30718 Neighboring gene predicted gene, 24887 Neighboring gene RAB11 family interacting protein 4 (class II), opposite strand 2 Neighboring gene nuclear encoded tRNA threonine 3 (anticodon CGT) Neighboring gene predicted gene 11205 Neighboring gene microRNA 193a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1821

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytic recycling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within neural retina development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of G1 to G0 transition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in cleavage furrow IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cleavage furrow ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endocytic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    is_active_in recycling endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in recycling endosome membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    rab11 family-interacting protein 4
    Names
    FIP4-Rab11
    mRab11-FIP4A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175543.3NP_780752.1  rab11 family-interacting protein 4

      See identical proteins and their annotated locations for NP_780752.1

      Status: PROVISIONAL

      Source sequence(s)
      AK046734
      Consensus CDS
      CCDS25123.1
      UniProtKB/Swiss-Prot
      Q8BQP8
      Related
      ENSMUSP00000017783.7, ENSMUST00000017783.13
      Conserved Domains (3) summary
      pfam09457
      Location:594634
      RBD-FIP; FIP domain
      pfam13499
      Location:2178
      EF-hand_7; EF-hand domain pair
      cl03075
      Location:426510
      GrpE; nucleotide exchange factor GrpE

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      79481847..79588842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006533403.2XP_006533466.1  rab11 family-interacting protein 4 isoform X1

      Conserved Domains (3) summary
      COG1196
      Location:315545
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:571611
      RBD-FIP; FIP domain
      pfam13499
      Location:2078
      EF-hand_7; EF-hand domain pair
    2. XM_036156717.1XP_036012610.1  rab11 family-interacting protein 4 isoform X2

      Conserved Domains (2) summary
      TIGR02168
      Location:278560
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam09457
      Location:535575
      RBD-FIP; FIP domain
    3. XM_036156719.1XP_036012612.1  rab11 family-interacting protein 4 isoform X5

      Conserved Domains (1) summary
      pfam13499
      Location:2078
      EF-hand_7; EF-hand domain pair
    4. XM_030246035.2XP_030101895.1  rab11 family-interacting protein 4 isoform X4

      Conserved Domains (2) summary
      COG1196
      Location:199429
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:455495
      RBD-FIP; FIP domain
    5. XM_006533404.4XP_006533467.1  rab11 family-interacting protein 4 isoform X3

      Conserved Domains (2) summary
      COG1196
      Location:236466
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam09457
      Location:492532
      RBD-FIP; FIP domain
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