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    OR7E24 olfactory receptor family 7 subfamily E member 24 [ Homo sapiens (human) ]

    Gene ID: 26648, updated on 17-Sep-2024

    Summary

    Official Symbol
    OR7E24provided by HGNC
    Official Full Name
    olfactory receptor family 7 subfamily E member 24provided by HGNC
    Primary source
    HGNC:HGNC:8396
    See related
    Ensembl:ENSG00000237521 AllianceGenome:HGNC:8396
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSHT2; OR19-8; OR7E24P; OR7E24Q
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR7E24 in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9206488..9252625)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9332685..9378827)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9358020..9363301)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily E member 16 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 25 pseudogene Neighboring gene olfactory receptor family 7 subfamily D member 4 Neighboring gene olfactory receptor family 7 subfamily D member 11 pseudogene Neighboring gene olfactory receptor family 7 subfamily D member 1 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 18 pseudogene Neighboring gene olfactory receptor family 7 subfamily E member 19 pseudogene

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 7E24
    Names
    olfactory receptor OR19-14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079935.2NP_001073404.1  olfactory receptor 7E24 isoform 1

      See identical proteins and their annotated locations for NP_001073404.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC006271
      Consensus CDS
      CCDS45955.1
      UniProtKB/Swiss-Prot
      B9EJD9, Q6IFN5, Q9UPJ1
      UniProtKB/TrEMBL
      A0A126GVS1
      Related
      ENSP00000387523.1, ENST00000456448.3
      Conserved Domains (2) summary
      pfam00001
      Location:59308
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:49322
      7tm_4; Olfactory receptor
    2. NM_001386108.1NP_001373037.1  olfactory receptor 7E24 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC006271
      Consensus CDS
      CCDS92506.1
      UniProtKB/TrEMBL
      A0A126GVS1, A0A2R8Y4Q1
      Related
      ENSP00000494223.1, ENST00000641946.1
      Conserved Domains (1) summary
      cd15234
      Location:39315
      7tmA_OR7-like; olfactory receptor family 7 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      9206488..9252625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047438597.1XP_047294553.1  olfactory receptor 7E24 isoform X3

      UniProtKB/TrEMBL
      O43789
    2. XM_047438594.1XP_047294550.1  olfactory receptor 7E24 isoform X1

      UniProtKB/TrEMBL
      A0A126GVS1
    3. XM_047438596.1XP_047294552.1  olfactory receptor 7E24 isoform X3

      UniProtKB/TrEMBL
      O43789
    4. XM_047438598.1XP_047294554.1  olfactory receptor 7E24 isoform X3

      UniProtKB/TrEMBL
      O43789
    5. XM_047438595.1XP_047294551.1  olfactory receptor 7E24 isoform X2

      UniProtKB/TrEMBL
      A0A126GVS1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      9332685..9378827
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054320518.1XP_054176493.1  olfactory receptor 7E24 isoform X3

      UniProtKB/TrEMBL
      O43789
    2. XM_054320515.1XP_054176490.1  olfactory receptor 7E24 isoform X1

      UniProtKB/TrEMBL
      A0A126GVS1
    3. XM_054320517.1XP_054176492.1  olfactory receptor 7E24 isoform X3

      UniProtKB/TrEMBL
      O43789
    4. XM_054320519.1XP_054176494.1  olfactory receptor 7E24 isoform X3

      UniProtKB/TrEMBL
      O43789
    5. XM_054320516.1XP_054176491.1  olfactory receptor 7E24 isoform X2

      UniProtKB/TrEMBL
      A0A126GVS1