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    Psma4 proteasome subunit alpha 4 [ Mus musculus (house mouse) ]

    Gene ID: 26441, updated on 22-Aug-2021

    Summary

    Official Symbol
    Psma4provided by MGI
    Official Full Name
    proteasome subunit alpha 4provided by MGI
    Primary source
    MGI:MGI:1347060
    See related
    Ensembl:ENSMUSG00000032301
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C9
    Expression
    Ubiquitous expression in placenta adult (RPKM 71.5), CNS E11.5 (RPKM 59.3) and 27 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Psma4 in Genome Data Viewer
    Location:
    9; 9 B
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (54858065..54865318)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (54950781..54958034)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (54798666..54805837)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene iron responsive element binding protein 2 Neighboring gene hydroxylysine kinase 1 Neighboring gene cDNA sequence AY074887 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 5 Neighboring gene cholinergic receptor, nicotinic, alpha polypeptide 3 Neighboring gene cholinergic receptor, nicotinic, beta polypeptide 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables threonine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in proteasomal protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in proteolysis involved in cellular protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in P-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of proteasome complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of proteasome core complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of proteasome core complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome core complex, alpha-subunit complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of proteasome core complex, alpha-subunit complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    proteasome subunit alpha type-4
    Names
    macropain subunit C9
    multicatalytic endopeptidase complex subunit C9
    proteasome (prosome, macropain) subunit, alpha type 4
    proteasome component C9
    proteasome subunit L
    NP_036096.1
    XP_006511261.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011966.3NP_036096.1  proteasome subunit alpha type-4

      See identical proteins and their annotated locations for NP_036096.1

      Status: PROVISIONAL

      Source sequence(s)
      AC161264
      Consensus CDS
      CCDS40643.1
      UniProtKB/Swiss-Prot
      Q9R1P0
      Related
      ENSMUSP00000034848.8, ENSMUST00000034848.14
      Conserved Domains (1) summary
      cd03752
      Location:3216
      proteasome_alpha_type_4; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      54858065..54865318
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511198.4XP_006511261.1  proteasome subunit alpha type-4 isoform X1

      See identical proteins and their annotated locations for XP_006511261.1

      UniProtKB/Swiss-Prot
      Q9R1P0
      Related
      ENSMUSP00000126844.2, ENSMUST00000172407.8
      Conserved Domains (1) summary
      cd03752
      Location:3216
      proteasome_alpha_type_4; The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming ...
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