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    Cetn2 centrin 2 [ Mus musculus (house mouse) ]

    Gene ID: 26370, updated on 3-Feb-2019

    Summary

    Official Symbol
    Cetn2provided by MGI
    Official Full Name
    centrin 2provided by MGI
    Primary source
    MGI:MGI:1347085
    See related
    Ensembl:ENSMUSG00000031347
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Calt; AI326150; caltractin; 1110034A02Rik
    Expression
    Broad expression in CNS E11.5 (RPKM 20.4), bladder adult (RPKM 16.1) and 22 other tissues See more
    Orthologs

    Genomic context

    See Cetn2 in Genome Data Viewer
    Location:
    X A7.3; X 37.29 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) X NC_000086.7 (72913565..72918344, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (70158904..70163683, complement)

    Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene gamma-aminobutyric acid (GABA) A receptor, subunit theta Neighboring gene melanoma antigen, family A, 9, pseudogene Neighboring gene NAD(P) dependent steroid dehydrogenase-like Neighboring gene zinc finger protein 185 Neighboring gene microRNA 2137

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein beta/gamma-subunit complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion binding TAS
    Traceable Author Statement
    more info
    PubMed 
    heterotrimeric G-protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    centriole replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centriole replication ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide-excision repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleotide-excision repair ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    spermatogenesis IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    XPC complex ISO
    Inferred from Sequence Orthology
    more info
     
    centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centriole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centriole ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    photoreceptor connecting cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    centrin-2
    Names
    caltractin, 20 kDa calcium binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019405.6NP_062278.2  centrin-2

      See identical proteins and their annotated locations for NP_062278.2

      Status: PROVISIONAL

      Source sequence(s)
      AK004081
      Consensus CDS
      CCDS41003.1
      UniProtKB/Swiss-Prot
      Q9R1K9
      Related
      ENSMUSP00000110198.3, ENSMUST00000114551.9
      Conserved Domains (2) summary
      PTZ00183
      Location:16172
      PTZ00183; centrin; Provisional
      cd00051
      Location:105167
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000086.7 Reference GRCm38.p4 C57BL/6J

      Range
      72913565..72918344 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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