Format

Send to:

Choose Destination
    • Showing Current items.

    Plekhg3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3 [ Mus musculus (house mouse) ]

    Gene ID: 263406, updated on 23-Jun-2021

    Summary

    Official Symbol
    Plekhg3provided by MGI
    Official Full Name
    pleckstrin homology domain containing, family G (with RhoGef domain) member 3provided by MGI
    Primary source
    MGI:MGI:2388284
    See related
    Ensembl:ENSMUSG00000052609
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BC030417
    Expression
    Ubiquitous expression in kidney adult (RPKM 15.9), bladder adult (RPKM 13.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Plekhg3 in Genome Data Viewer
    Location:
    12; 12 C3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (76580087..76627261)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (76533303..76580489)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (77634547..77680026)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40445 Neighboring gene microRNA 5135 Neighboring gene expressed sequence AI463170 Neighboring gene spectrin beta, erythrocytic Neighboring gene churchill domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC40768

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    pleckstrin homology domain-containing family G member 3
    Names
    PH domain-containing family G member 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153804.4NP_722499.4  pleckstrin homology domain-containing family G member 3

      See identical proteins and their annotated locations for NP_722499.4

      Status: VALIDATED

      Source sequence(s)
      AC163033, AK080928, AK162025, AK172977
      Consensus CDS
      CCDS25994.1
      UniProtKB/Swiss-Prot
      Q4VAC9
      Related
      ENSMUSP00000074729.5, ENSMUST00000075249.6
      Conserved Domains (3) summary
      cd13243
      Location:253396
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
      pfam00169
      Location:317393
      PH; PH domain
      pfam00621
      Location:97271
      RhoGEF; RhoGEF domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      76580087..76627261
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515873.5XP_006515936.1  pleckstrin homology domain-containing family G member 3 isoform X5

      See identical proteins and their annotated locations for XP_006515936.1

      Conserved Domains (2) summary
      smart00325
      Location:97271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:253396
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    2. XM_006515875.5XP_006515938.1  pleckstrin homology domain-containing family G member 3 isoform X6

      UniProtKB/Swiss-Prot
      Q4VAC9
      Related
      ENSMUSP00000151851.2, ENSMUST00000219063.2
      Conserved Domains (2) summary
      smart00325
      Location:97271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:253396
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    3. XM_006515870.4XP_006515933.1  pleckstrin homology domain-containing family G member 3 isoform X2

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    4. XM_006515880.3XP_006515943.1  pleckstrin homology domain-containing family G member 3 isoform X10

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    5. XM_006515869.3XP_006515932.1  pleckstrin homology domain-containing family G member 3 isoform X1

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    6. XM_006515878.3XP_006515941.1  pleckstrin homology domain-containing family G member 3 isoform X9

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    7. XM_006515876.3XP_006515939.1  pleckstrin homology domain-containing family G member 3 isoform X7

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    8. XM_006515877.3XP_006515940.1  pleckstrin homology domain-containing family G member 3 isoform X8

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    9. XM_006515871.3XP_006515934.1  pleckstrin homology domain-containing family G member 3 isoform X3

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    10. XM_006515872.3XP_006515935.1  pleckstrin homology domain-containing family G member 3 isoform X4

      Conserved Domains (2) summary
      smart00325
      Location:118292
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:274417
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    11. XM_006515874.4XP_006515937.1  pleckstrin homology domain-containing family G member 3 isoform X5

      See identical proteins and their annotated locations for XP_006515937.1

      Conserved Domains (2) summary
      smart00325
      Location:97271
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd13243
      Location:253396
      PH_PLEKHG1_G2_G3; Pleckstrin homology domain-containing family G members 1, 2, and 3 pleckstrin homology (PH) domain
    Support Center