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    Cables2 CDK5 and Abl enzyme substrate 2 [ Mus musculus (house mouse) ]

    Gene ID: 252966, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cables2provided by MGI
    Official Full Name
    CDK5 and Abl enzyme substrate 2provided by MGI
    Primary source
    MGI:MGI:2182335
    See related
    Ensembl:ENSMUSG00000038990
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ik3-2
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 17.8), CNS E18 (RPKM 17.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cables2 in Genome Data Viewer
    Location:
    2; 2 H4
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (180258539..180273490, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (179993244..180008170, complement)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene microRNA 7005 Neighboring gene laminin, alpha 5 Neighboring gene microRNA 3091 Neighboring gene ribosomal protein S21 Neighboring gene RBBP8 N-terminal like Neighboring gene predicted gene, 29943

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    CDK5 and ABL1 enzyme substrate 2
    Names
    interactor with CDK3 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145851.2NP_665850.2  CDK5 and ABL1 enzyme substrate 2

      See identical proteins and their annotated locations for NP_665850.2

      Status: VALIDATED

      Source sequence(s)
      AL663027
      Consensus CDS
      CCDS38377.1
      UniProtKB/Swiss-Prot
      Q8K3M5
      Related
      ENSMUSP00000104519.1, ENSMUST00000108891.1
      Conserved Domains (1) summary
      cd00043
      Location:360416
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      180258539..180273490 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500629.1XP_006500692.1  CDK5 and ABL1 enzyme substrate 2 isoform X1

      Conserved Domains (1) summary
      cd00043
      Location:336392
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    RNA

    1. XR_001782621.1 RNA Sequence

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