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    Naxe NAD(P)HX epimerase [ Mus musculus (house mouse) ]

    Gene ID: 246703, updated on 23-Jun-2021

    Summary

    Official Symbol
    Naxeprovided by MGI
    Official Full Name
    NAD(P)HX epimeraseprovided by MGI
    Primary source
    MGI:MGI:2180167
    See related
    Ensembl:ENSMUSG00000028070
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI; AP; AIBP; AI-BP; ESTM3; ESTM37; Apoa1bp; Apoa1ip; AA087124
    Expression
    Ubiquitous expression in kidney adult (RPKM 55.9), adrenal adult (RPKM 49.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Naxe in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87963827..87965851, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (88056520..88058542, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (87860445..87862417, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 19439 Neighboring gene G patch domain containing 4 Neighboring gene tetratricopeptide repeat domain 24 Neighboring gene IQ motif containing GTPase activating protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables NADHX epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables NADHX epimerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables NADPHX epimerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in membrane raft distribution ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nicotinamide nucleotide metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cholesterol efflux ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sprouting angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    NAD(P)H-hydrate epimerase
    Names
    apoA-I binding protein
    apolipoprotein A-I binding protein
    apolipoprotein A-I interacting protein
    NP_659146.1
    XP_006501580.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144897.3NP_659146.1  NAD(P)H-hydrate epimerase precursor

      See identical proteins and their annotated locations for NP_659146.1

      Status: PROVISIONAL

      Source sequence(s)
      AC137525
      Consensus CDS
      CCDS17464.1
      UniProtKB/Swiss-Prot
      Q8K4Z3
      Related
      ENSMUSP00000029708.7, ENSMUST00000029708.8
      Conserved Domains (1) summary
      cl00318
      Location:46281
      YjeF_N; YjeF-related protein N-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      87963827..87965851 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501517.5XP_006501580.2  NAD(P)H-hydrate epimerase isoform X1

      See identical proteins and their annotated locations for XP_006501580.2

      Conserved Domains (1) summary
      PLN03049
      Location:50167
      PLN03049; pyridoxine (pyridoxamine) 5'-phosphate oxidase; Provisional

    RNA

    1. XR_004941327.1 RNA Sequence

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