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    Atxn7 ataxin 7 [ Mus musculus (house mouse) ]

    Gene ID: 246103, updated on 23-Jun-2021

    Summary

    Official Symbol
    Atxn7provided by MGI
    Official Full Name
    ataxin 7provided by MGI
    Primary source
    MGI:MGI:2179277
    See related
    Ensembl:ENSMUSG00000021738
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sc; Sca7; atax; AI627028; ataxin-7; A430107N12Rik
    Expression
    Ubiquitous expression in lung adult (RPKM 4.5), bladder adult (RPKM 4.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Atxn7 in Genome Data Viewer
    Location:
    14; 14 A1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (8358367..8508324, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (13961283..14107316)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (14845005..14939816)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene olfactory receptor 720 Neighboring gene proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 Neighboring gene predicted gene, 53821 Neighboring gene THO complex 7 Neighboring gene predicted gene 11100 Neighboring gene predicted gene 281 Neighboring gene zinc finger, AN1-type domain 5 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ataxin-7
    Names
    spinocerebellar ataxia 7 homolog
    spinocerebellar ataxia type 7 protein homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_139227.4NP_631973.3  ataxin-7

      See identical proteins and their annotated locations for NP_631973.3

      Status: VALIDATED

      Source sequence(s)
      AC116479, AI508474, AK046679, BP758427, CJ101662
      Consensus CDS
      CCDS26823.1
      UniProtKB/Swiss-Prot
      Q8R4I1
      Related
      ENSMUSP00000022257.3, ENSMUST00000022257.4
      Conserved Domains (1) summary
      pfam08313
      Location:319378
      SCA7; SCA7, zinc-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      8358367..8508324 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518018.5XP_006518081.1  ataxin-7 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:359593
      PHA03247; large tegument protein UL36; Provisional
      pfam08313
      Location:296355
      SCA7; zinc-binding domain
      pfam15912
      Location:367445
      VIR_N; Virilizer, N-terminal
    2. XM_006518015.5XP_006518078.1  ataxin-7 isoform X1

      See identical proteins and their annotated locations for XP_006518078.1

      UniProtKB/TrEMBL
      A0A286YDW9
      Conserved Domains (3) summary
      PHA03247
      Location:382616
      PHA03247; large tegument protein UL36; Provisional
      pfam08313
      Location:319378
      SCA7; zinc-binding domain
      pfam15912
      Location:390468
      VIR_N; Virilizer, N-terminal
    3. XM_036158598.1XP_036014491.1  ataxin-7 isoform X3

      Conserved Domains (2) summary
      PHA03247
      Location:276350
      PHA03247; large tegument protein UL36; Provisional
      pfam08313
      Location:202261
      SCA7; zinc-binding domain
    4. XM_006518017.4XP_006518080.1  ataxin-7 isoform X1

      See identical proteins and their annotated locations for XP_006518080.1

      UniProtKB/TrEMBL
      A0A286YDW9
      Related
      ENSMUSP00000153613.2, ENSMUST00000223714.2
      Conserved Domains (3) summary
      PHA03247
      Location:382616
      PHA03247; large tegument protein UL36; Provisional
      pfam08313
      Location:319378
      SCA7; zinc-binding domain
      pfam15912
      Location:390468
      VIR_N; Virilizer, N-terminal
    5. XM_036158599.1XP_036014492.1  ataxin-7 isoform X4

      Conserved Domains (2) summary
      PHA03247
      Location:173247
      PHA03247; large tegument protein UL36; Provisional
      pfam08313
      Location:99158
      SCA7; zinc-binding domain
    6. XM_030247817.2XP_030103677.1  ataxin-7 isoform X5

      Conserved Domains (3) summary
      PHA03247
      Location:162396
      PHA03247; large tegument protein UL36; Provisional
      pfam08313
      Location:99158
      SCA7; zinc-binding domain
      pfam15912
      Location:170248
      VIR_N; Virilizer, N-terminal

    RNA

    1. XR_004938401.1 RNA Sequence

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