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    Rttn rotatin [ Mus musculus (house mouse) ]

    Gene ID: 246102, updated on 16-Jul-2021

    Summary

    Official Symbol
    Rttnprovided by MGI
    Official Full Name
    rotatinprovided by MGI
    Primary source
    MGI:MGI:2179288
    See related
    Ensembl:ENSMUSG00000023066
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI666264; D230040K24; 4921538A15Rik; C530033I08Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 2.5), CNS E11.5 (RPKM 2.4) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Rttn in Genome Data Viewer
    Location:
    18; 18 E4
    Exon count:
    53
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (88989860..89149140)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (88971736..89131014)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (89141182..89300406)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene high mobility group box 1-like pseudogene Neighboring gene suppressor of cytokine signaling 6 Neighboring gene microRNA 6359 Neighboring gene CD226 antigen Neighboring gene docking protein 6 Neighboring gene predicted gene, 18279

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 
    • Gene trapped (1)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in centriole replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in centriole-centriole cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in ciliary basal body organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cilium organization IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within determination of left/right symmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175542.3NP_780751.2  rotatin

      See identical proteins and their annotated locations for NP_780751.2

      Status: VALIDATED

      Source sequence(s)
      AF265232, BC023916
      Consensus CDS
      CCDS29390.1
      UniProtKB/Swiss-Prot
      Q8R4Y8
      Related
      ENSMUSP00000023828.8, ENSMUST00000023828.9
      Conserved Domains (1) summary
      pfam14726
      Location:16112
      RTTN_N; Rotatin, an armadillo repeat protein, centriole functioning

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      88989860..89149140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161149.1XP_036017042.1  rotatin isoform X3

      Conserved Domains (1) summary
      pfam14726
      Location:16112
      RTTN_N; Rotatin, an armadillo repeat protein, centriole functioning
    2. XM_030250463.2XP_030106323.1  rotatin isoform X1

    3. XM_011247080.4XP_011245382.1  rotatin isoform X2

    4. XM_036161150.1XP_036017043.1  rotatin isoform X4

    RNA

    1. XR_386368.3 RNA Sequence

    2. XR_001782364.1 RNA Sequence

    3. XR_001782365.2 RNA Sequence

    4. XR_386369.5 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178063.2: Suppressed sequence

      Description
      NM_178063.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    2. NM_178064.2: Suppressed sequence

      Description
      NM_178064.2: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
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