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    Rbbp7 retinoblastoma binding protein 7, chromatin remodeling factor [ Mus musculus (house mouse) ]

    Gene ID: 245688, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rbbp7provided by MGI
    Official Full Name
    retinoblastoma binding protein 7, chromatin remodeling factorprovided by MGI
    Primary source
    MGI:MGI:1194910
    See related
    Ensembl:ENSMUSG00000031353
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mRbAp46; AA409861; AI173248; AU019541; BB114024
    Expression
    Broad expression in placenta adult (RPKM 217.3), liver E18 (RPKM 180.1) and 21 other tissues See more
    Orthologs
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    Genomic context

    See Rbbp7 in Genome Data Viewer
    Location:
    X; X F4
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (161543368..161562086)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (162760372..162779090)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (159198304..159217022)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene 15201 Neighboring gene predicted gene, 23786 Neighboring gene taxilin gamma Neighboring gene pyruvate kinase, muscle pseudogene Neighboring gene predicted gene, 23901

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of ESC/E(Z) complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ESC/E(Z) complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of NuRD complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of NuRD complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    part_of histone deacetylase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    histone-binding protein RBBP7
    Names
    G1/S transition control protein-binding protein
    RBBP-7
    histone acetyltransferase type B subunit 2
    nucleosome-remodeling factor subunit RBAP46
    retinoblastoma-binding protein 7
    retinoblastoma-binding protein p46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009031.3NP_033057.3  histone-binding protein RBBP7

      See identical proteins and their annotated locations for NP_033057.3

      Status: VALIDATED

      Source sequence(s)
      AK078349, AK135779, CA556887
      Consensus CDS
      CCDS30509.1
      UniProtKB/Swiss-Prot
      Q60973
      UniProtKB/TrEMBL
      Q8C5H3
      Related
      ENSMUSP00000033720.6, ENSMUST00000033720.12
      Conserved Domains (3) summary
      sd00039
      Location:127174
      7WD40; WD40 repeat [structural motif]
      pfam12265
      Location:1887
      CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
      cl29593
      Location:122402
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      161543368..161562086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251353.1XP_030107213.1  histone-binding protein RBBP7 isoform X1

      Conserved Domains (3) summary
      sd00039
      Location:93140
      7WD40; WD40 repeat [structural motif]
      pfam12265
      Location:153
      CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex
      cl29593
      Location:88368
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
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