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    Peak1 pseudopodium-enriched atypical kinase 1 [ Mus musculus (house mouse) ]

    Gene ID: 244895, updated on 31-Jan-2019

    Summary

    Official Symbol
    Peak1provided by MGI
    Official Full Name
    pseudopodium-enriched atypical kinase 1provided by MGI
    Primary source
    MGI:MGI:2442366
    See related
    Ensembl:ENSMUSG00000074305
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SGK269; AA690169; BE132841; mKIAA2002; 9530046P14; 1110049L02Rik; C230081A13Rik
    Expression
    Ubiquitous expression in lung adult (RPKM 5.8), cerebellum adult (RPKM 5.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Peak1 in Genome Data Viewer
    Location:
    9; 9 B
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (56201126..56418230, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (56048933..56265857, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene proline-serine-threonine phosphatase-interacting protein 1 Neighboring gene tetraspanin 3 Neighboring gene pseudopodium-enriched atypical kinase 1, opposite strand Neighboring gene high mobility group 20A Neighboring gene ubiquitin-conjugating enzyme E2S pseudogene Neighboring gene predicted gene, 31529

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    non-membrane spanning protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    inactive tyrosine-protein kinase PEAK1; pseudopodium-enriched atypical kinase 1
    Names
    NKF3 kinase family member
    sugen kinase 269
    tyrosine-protein kinase SgK269
    NP_766512.2
    XP_006511230.1
    XP_006511231.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172924.3NP_766512.2  inactive tyrosine-protein kinase PEAK1

      See identical proteins and their annotated locations for NP_766512.2

      Status: VALIDATED

      Source sequence(s)
      AC160935, AK004211, AK035440, AK048912, AK173328, AW457766, CJ186507
      Consensus CDS
      CCDS52804.1
      UniProtKB/Swiss-Prot
      Q69Z38
      Related
      ENSMUSP00000109901.2, ENSMUST00000061552.14
      Conserved Domains (1) summary
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      56201126..56418230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511168.3XP_006511231.1  pseudopodium-enriched atypical kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_006511231.1

      UniProtKB/Swiss-Prot
      Q69Z38
      Conserved Domains (1) summary
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain
    2. XM_006511167.3XP_006511230.1  pseudopodium-enriched atypical kinase 1 isoform X1

      See identical proteins and their annotated locations for XP_006511230.1

      UniProtKB/Swiss-Prot
      Q69Z38
      Conserved Domains (1) summary
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain
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