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    Peak1 pseudopodium-enriched atypical kinase 1 [ Mus musculus (house mouse) ]

    Gene ID: 244895, updated on 8-Aug-2021

    Summary

    Official Symbol
    Peak1provided by MGI
    Official Full Name
    pseudopodium-enriched atypical kinase 1provided by MGI
    Primary source
    MGI:MGI:2442366
    See related
    Ensembl:ENSMUSG00000074305
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SGK269; AA690169; BE132841; mKIAA2002; 9530046P14; 1110049L02Rik; C230081A13Rik
    Expression
    Ubiquitous expression in lung adult (RPKM 5.8), cerebellum adult (RPKM 5.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Peak1 in Genome Data Viewer
    Location:
    9; 9 B
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (56108410..56325972, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (56201126..56418222, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (56048933..56265857, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene proline-serine-threonine phosphatase-interacting protein 1 Neighboring gene tetraspanin 3 Neighboring gene pseudopodium-enriched atypical kinase 1, opposite strand Neighboring gene high mobility group 20A Neighboring gene ubiquitin-conjugating enzyme E2S pseudogene Neighboring gene predicted gene, 53524

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables non-membrane spanning protein tyrosine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    inactive tyrosine-protein kinase PEAK1
    Names
    NKF3 kinase family member
    sugen kinase 269
    tyrosine-protein kinase SgK269
    NP_766512.2
    XP_006511230.1
    XP_006511231.1
    XP_036010901.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172924.3NP_766512.2  inactive tyrosine-protein kinase PEAK1

      See identical proteins and their annotated locations for NP_766512.2

      Status: VALIDATED

      Source sequence(s)
      AC160935, AK004211, AK035440, AK048912, AK173328, AW457766, CJ186507
      Consensus CDS
      CCDS52804.1
      UniProtKB/Swiss-Prot
      Q69Z38
      Related
      ENSMUSP00000109901.3, ENSMUST00000061552.15
      Conserved Domains (2) summary
      pfam05109
      Location:475853
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      56108410..56325972 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155008.1XP_036010901.1  inactive tyrosine-protein kinase PEAK1 isoform X1

      Conserved Domains (2) summary
      pfam05109
      Location:475853
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain
    2. XM_006511168.5XP_006511231.1  inactive tyrosine-protein kinase PEAK1 isoform X1

      See identical proteins and their annotated locations for XP_006511231.1

      UniProtKB/Swiss-Prot
      Q69Z38
      Conserved Domains (2) summary
      pfam05109
      Location:475853
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain
    3. XM_006511167.5XP_006511230.1  inactive tyrosine-protein kinase PEAK1 isoform X1

      See identical proteins and their annotated locations for XP_006511230.1

      UniProtKB/Swiss-Prot
      Q69Z38
      Conserved Domains (2) summary
      pfam05109
      Location:475853
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      cl21453
      Location:14921657
      PKc_like; Protein Kinases, catalytic domain
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