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    Scaper S phase cyclin A-associated protein in the ER [ Mus musculus (house mouse) ]

    Gene ID: 244891, updated on 8-Sep-2024

    Summary

    Official Symbol
    Scaperprovided by MGI
    Official Full Name
    S phase cyclin A-associated protein in the ERprovided by MGI
    Primary source
    MGI:MGI:1925976
    See related
    Ensembl:ENSMUSG00000034007 AllianceGenome:MGI:1925976
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp291; C430017I08; D530014O03Rik
    Summary
    Predicted to be located in cytosol and nuclear speck. Is expressed in brain; early conceptus; eye; and genitourinary system. Orthologous to human SCAPER (S-phase cyclin A associated protein in the ER). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 5.9), CNS E18 (RPKM 5.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Scaper in Genome Data Viewer
    Location:
    9 B; 9 30.13 cM
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (55457163..55845505, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (55549879..55938221, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_24191 Neighboring gene STARR-seq mESC enhancer starr_24192 Neighboring gene predicted gene 5917 Neighboring gene predicted gene, 23407 Neighboring gene insulin related protein 2 (islet 2) Neighboring gene STARR-seq mESC enhancer starr_24193 Neighboring gene ribosomal protein L13 pseudogene Neighboring gene STARR-positive B cell enhancer mm9_chr9:55546201-55546502 Neighboring gene predicted gene, 39342 Neighboring gene STARR-seq mESC enhancer starr_24195 Neighboring gene STARR-positive B cell enhancer ABC_E6735 Neighboring gene STARR-seq mESC enhancer starr_24197 Neighboring gene RIKEN cDNA 4930563M21 gene Neighboring gene ring finger protein 19A pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    S phase cyclin A-associated protein in the endoplasmic reticulum
    Names
    zinc finger protein 291

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081341.2NP_001074810.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform 1

      See identical proteins and their annotated locations for NP_001074810.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC107819, AC116699, AC159901, AC164972, CT025567
      Consensus CDS
      CCDS52802.1
      UniProtKB/TrEMBL
      F8VQ70, Q69ZJ3
      Related
      ENSMUSP00000149750.2, ENSMUST00000217647.2
      Conserved Domains (2) summary
      PTZ00121
      Location:536910
      PTZ00121; MAEBL; Provisional
      pfam16501
      Location:89185
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    2. NM_001357652.1NP_001344581.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC107819, AC116699, AC159901, AC164972, CT025567
      Consensus CDS
      CCDS90576.1
      UniProtKB/TrEMBL
      B2RXS3, Q69ZJ3
      Related
      ENSMUSP00000149050.2, ENSMUST00000214747.2
      Conserved Domains (2) summary
      PTZ00121
      Location:530904
      PTZ00121; MAEBL; Provisional
      pfam16501
      Location:89185
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    3. NM_001357653.1NP_001344582.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC116699, AK021288
      UniProtKB/TrEMBL
      Q8C1F7

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      55457163..55845505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030244383.1XP_030100243.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X2

      UniProtKB/TrEMBL
      B2RXS3, Q69ZJ3
      Conserved Domains (2) summary
      PTZ00121
      Location:530904
      PTZ00121; MAEBL; Provisional
      pfam16501
      Location:89185
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    2. XM_011242747.3XP_011241049.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X1

      See identical proteins and their annotated locations for XP_011241049.1

      UniProtKB/TrEMBL
      F8VQ70, Q69ZJ3
      Conserved Domains (2) summary
      PTZ00121
      Location:536910
      PTZ00121; MAEBL; Provisional
      pfam16501
      Location:89185
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    3. XM_030244384.1XP_030100244.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X2

      UniProtKB/TrEMBL
      B2RXS3, Q69ZJ3
      Conserved Domains (2) summary
      PTZ00121
      Location:530904
      PTZ00121; MAEBL; Provisional
      pfam16501
      Location:89185
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
    4. XM_011242748.4XP_011241050.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X1

      See identical proteins and their annotated locations for XP_011241050.1

      UniProtKB/TrEMBL
      F8VQ70, Q69ZJ3
      Conserved Domains (2) summary
      PTZ00121
      Location:536910
      PTZ00121; MAEBL; Provisional
      pfam16501
      Location:89185
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175536.2: Suppressed sequence

      Description
      NM_175536.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.