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    Scaper S phase cyclin A-associated protein in the ER [ Mus musculus (house mouse) ]

    Gene ID: 244891, updated on 31-Jan-2019

    Summary

    Official Symbol
    Scaperprovided by MGI
    Official Full Name
    S phase cyclin A-associated protein in the ERprovided by MGI
    Primary source
    MGI:MGI:1925976
    See related
    Ensembl:ENSMUSG00000034007
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Zfp291; C430017I08; D530014O03Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 5.9), CNS E18 (RPKM 5.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Scaper in Genome Data Viewer
    Location:
    9; 9 B
    Exon count:
    34
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (55549879..55938158, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (55397690..55785922, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene 5917 Neighboring gene insulin related protein 2 (islet 2) Neighboring gene ribosomal protein L13 pseudogene Neighboring gene predicted gene, 39342 Neighboring gene kinesin-like protein KIF23 Neighboring gene RIKEN cDNA 4930563M21 gene Neighboring gene ring finger protein 19A pseudogene Neighboring gene leucine zipper transcription factor-like 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    S phase cyclin A-associated protein in the endoplasmic reticulum
    Names
    zinc finger protein 291

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081341.2NP_001074810.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform 1

      See identical proteins and their annotated locations for NP_001074810.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC107819, AC116699, AC159901, AC164972, CT025567
      Consensus CDS
      CCDS52802.1
      UniProtKB/TrEMBL
      F8VQ70
      Related
      ENSMUSP00000149750.1, ENSMUST00000217647.1
      Conserved Domains (6) summary
      pfam07909
      Location:396906
      DUF1663; Protein of unknown function (DUF1663)
      smart00451
      Location:789821
      ZnF_U1; U1-like zinc finger
      pfam00836
      Location:528625
      Stathmin; Stathmin family
      pfam16501
      Location:88183
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cd16269
      Location:759769
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:669773
      GBP_C; Guanylate-binding protein, C-terminal domain
    2. NM_001357652.1NP_001344581.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC107819, AC116699, AC159901, AC164972, CT025567
      Conserved Domains (2) summary
      pfam16501
      Location:88183
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cl26511
      Location:530904
      Neuromodulin_N; Gap junction protein N-terminal region
    3. NM_001357653.1NP_001344582.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC116699, AK021288

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      55549879..55938158 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511166.3XP_006511229.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X2

      UniProtKB/TrEMBL
      B2RXS3
      Related
      ENSMUSP00000149050.1, ENSMUST00000214747.1
      Conserved Domains (2) summary
      pfam16501
      Location:88183
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cl26511
      Location:530904
      Neuromodulin_N; Gap junction protein N-terminal region
    2. XM_011242747.2XP_011241049.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X1

      See identical proteins and their annotated locations for XP_011241049.1

      UniProtKB/TrEMBL
      F8VQ70
      Related
      ENSMUSP00000043411.8, ENSMUST00000037408.8
      Conserved Domains (6) summary
      pfam07909
      Location:396906
      DUF1663; Protein of unknown function (DUF1663)
      smart00451
      Location:789821
      ZnF_U1; U1-like zinc finger
      pfam00836
      Location:528625
      Stathmin; Stathmin family
      pfam16501
      Location:88183
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cd16269
      Location:759769
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:669773
      GBP_C; Guanylate-binding protein, C-terminal domain
    3. XM_011242748.2XP_011241050.1  S phase cyclin A-associated protein in the endoplasmic reticulum isoform X1

      See identical proteins and their annotated locations for XP_011241050.1

      UniProtKB/TrEMBL
      F8VQ70
      Conserved Domains (6) summary
      pfam07909
      Location:396906
      DUF1663; Protein of unknown function (DUF1663)
      smart00451
      Location:789821
      ZnF_U1; U1-like zinc finger
      pfam00836
      Location:528625
      Stathmin; Stathmin family
      pfam16501
      Location:88183
      SCAPER_N; S phase cyclin A-associated protein in the endoplasmic reticulum
      cd16269
      Location:759769
      GBP_C; coiled coil [structural motif]
      cl20817
      Location:669773
      GBP_C; Guanylate-binding protein, C-terminal domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175536.2: Suppressed sequence

      Description
      NM_175536.2: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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