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    Arhgap20 Rho GTPase activating protein 20 [ Mus musculus (house mouse) ]

    Gene ID: 244867, updated on 23-Jun-2021

    Summary

    Official Symbol
    Arhgap20provided by MGI
    Official Full Name
    Rho GTPase activating protein 20provided by MGI
    Primary source
    MGI:MGI:2445175
    See related
    Ensembl:ENSMUSG00000053199
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RARhoGAP; mKIAA1391; 6530403F17Rik; A530023E23Rik
    Expression
    Broad expression in frontal lobe adult (RPKM 5.6), cortex adult (RPKM 5.5) and 16 other tissues See more
    Orthologs
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    Genomic context

    See Arhgap20 in Genome Data Viewer
    Location:
    9; 9 A5.3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (51676651..51765158)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (51765351..51853059)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (51573457..51661164)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein L9 pseudogene Neighboring gene predicted gene, 40520 Neighboring gene Rho GTPase activating protein 20, opposite strand Neighboring gene RIKEN cDNA 4933407I05 gene Neighboring gene predicted gene 6980 Neighboring gene ferredoxin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    rho GTPase-activating protein 20
    Names
    RA and RhoGAP domain-containing protein
    rho-type GTPase-activating protein 20

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175535.4NP_780744.2  rho GTPase-activating protein 20

      See identical proteins and their annotated locations for NP_780744.2

      Status: VALIDATED

      Source sequence(s)
      AC140363, AC162806
      Consensus CDS
      CCDS23177.1
      UniProtKB/Swiss-Prot
      Q6IFT4
      Related
      ENSMUSP00000065633.6, ENSMUST00000065496.12
      Conserved Domains (3) summary
      cd04402
      Location:362555
      RhoGAP_ARHGAP20; RhoGAP_ARHGAP20: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by ...
      cd13319
      Location:84180
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      pfam00788
      Location:198274
      RA; Ras association (RalGDS/AF-6) domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      51676651..51765158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155004.1XP_036010897.1  rho GTPase-activating protein 20 isoform X1

      Conserved Domains (3) summary
      cd04402
      Location:283476
      RhoGAP_ARHGAP20; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of ArhGAP20-like proteins. ArhGAP20, also known as KIAA1391 and RA-RhoGAP, contains a RhoGAP, a RA, and a PH domain, and ANXL repeats. ArhGAP20 is activated by Rap1 and induces ...
      cd13319
      Location:5101
      PH_RARhoGAP; RA and RhoGAP domain-containing protein Pleckstrin homology PH domain
      cd17115
      Location:115232
      RA_RHG20; Ras-associating (RA) domain found in Rho GTPase-activating protein 20 (RHG20) and similar proteins
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