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    Mctp2 multiple C2 domains, transmembrane 2 [ Mus musculus (house mouse) ]

    Gene ID: 244049, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mctp2provided by MGI
    Official Full Name
    multiple C2 domains, transmembrane 2provided by MGI
    Primary source
    MGI:MGI:2685335
    See related
    Ensembl:ENSMUSG00000032776
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm489
    Expression
    Broad expression in bladder adult (RPKM 1.2), colon adult (RPKM 0.7) and 20 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Mctp2 in Genome Data Viewer
    Location:
    7; 7 D1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (71727575..71956850, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (72077827..72307116, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (79222716..79451481, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930441H08 gene Neighboring gene RIKEN cDNA 1700011C11 gene Neighboring gene glycine cleavage system protein H (aminomethyl carrier) pseudogene Neighboring gene predicted gene, 36633 Neighboring gene predicted gene, 36696 Neighboring gene predicted gene, 39035 Neighboring gene ribosomal protein L17, pseudogene 10 Neighboring gene KAT8 regulatory NSL complex subunit 2, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of neurotransmitter secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    multiple C2 and transmembrane domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024703.1NP_001019874.1  multiple C2 and transmembrane domain-containing protein 2

      See identical proteins and their annotated locations for NP_001019874.1

      Status: PROVISIONAL

      Source sequence(s)
      BC086658
      Consensus CDS
      CCDS21361.1
      UniProtKB/Swiss-Prot
      Q5RJH2
      Related
      ENSMUSP00000078302.6, ENSMUST00000079323.8
      Conserved Domains (4) summary
      cd04042
      Location:195314
      C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08376
      Location:357469
      C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08377
      Location:509627
      C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      pfam08372
      Location:771824
      PRT_C; Plant phosphoribosyltransferase C-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      71727575..71956850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242581.2XP_030098441.1  multiple C2 and transmembrane domain-containing protein 2 isoform X1

      Conserved Domains (4) summary
      cd04042
      Location:195314
      C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08376
      Location:357469
      C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08377
      Location:509627
      C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      pfam08372
      Location:771824
      PRT_C; Plant phosphoribosyltransferase C-terminal
    2. XM_006540899.4XP_006540962.1  multiple C2 and transmembrane domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006540962.1

      UniProtKB/Swiss-Prot
      Q5RJH2
      Conserved Domains (4) summary
      cd04042
      Location:195314
      C2A_MCTP_PRT; C2 domain first repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08376
      Location:357469
      C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08377
      Location:509627
      C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      pfam08372
      Location:771824
      PRT_C; Plant phosphoribosyltransferase C-terminal
    3. XM_006540901.2XP_006540964.1  multiple C2 and transmembrane domain-containing protein 2 isoform X2

      Conserved Domains (4) summary
      cd08376
      Location:170282
      C2B_MCTP_PRT; C2 domain second repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      cd08377
      Location:322440
      C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      pfam08372
      Location:584637
      PRT_C; Plant phosphoribosyltransferase C-terminal
      cl14603
      Location:24127
      C2; C2 domain
    4. XM_011250864.1XP_011249166.1  multiple C2 and transmembrane domain-containing protein 2 isoform X3

      Conserved Domains (3) summary
      cd08377
      Location:97215
      C2C_MCTP_PRT; C2 domain third repeat found in Multiple C2 domain and Transmembrane region Proteins (MCTP)
      pfam08372
      Location:359412
      PRT_C; Plant phosphoribosyltransferase C-terminal
      cl14603
      Location:157
      C2; C2 domain
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