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    Zfp568 zinc finger protein 568 [ Mus musculus (house mouse) ]

    Gene ID: 243905, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp568provided by MGI
    Official Full Name
    zinc finger protein 568provided by MGI
    Primary source
    MGI:MGI:2142347
    See related
    Ensembl:ENSMUSG00000074221
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    cha; chato; C80731; Gm1691; Znf568
    Expression
    Broad expression in placenta adult (RPKM 18.4), limb E14.5 (RPKM 6.9) and 20 other tissues See more
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    Genomic context

    See Zfp568 in Genome Data Viewer
    Location:
    7; 7 B1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29683380..29727707)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29983955..30028282)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (30768974..30813301)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 570-like Neighboring gene macrophage migration inhibitory factor, pseudogene Neighboring gene predicted gene, 31735 Neighboring gene zinc finger protein 14 Neighboring gene zinc finger protein 82

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription cis-regulatory region binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables transcription corepressor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033355.3NP_001028527.2  zinc finger protein 568 isoform 1

      See identical proteins and their annotated locations for NP_001028527.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1, and encodes isoform (1). Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK143471, AK148548, BC082606, BE456949
      Consensus CDS
      CCDS21077.1
      UniProtKB/Swiss-Prot
      E9PYI1
      Related
      ENSMUSP00000118387.2, ENSMUST00000148442.8
      Conserved Domains (3) summary
      smart00349
      Location:3494
      KRAB; krueppel associated box
      COG5048
      Location:350665
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:589609
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001167872.1NP_001161344.1  zinc finger protein 568 isoform 1

      See identical proteins and their annotated locations for NP_001161344.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes isoform (1). Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK148548, BC082606, BE456949
      Consensus CDS
      CCDS21077.1
      UniProtKB/Swiss-Prot
      E9PYI1
      Conserved Domains (3) summary
      smart00349
      Location:3494
      KRAB; krueppel associated box
      COG5048
      Location:350665
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:589609
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001167873.1NP_001161345.1  zinc finger protein 568 isoform 2

      See identical proteins and their annotated locations for NP_001161345.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1, and encodes a protein (isoform 2) that is 1 aa shorter than isoform 1.
      Source sequence(s)
      AK148548, BC082606, BE456949
      Consensus CDS
      CCDS52176.1
      UniProtKB/Swiss-Prot
      E9PYI1
      Related
      ENSMUSP00000118823.2, ENSMUST00000146074.8
      Conserved Domains (6) summary
      smart00349
      Location:3494
      KRAB; krueppel associated box
      COG5048
      Location:198633
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:588608
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:418440
      zf-C2H2; Zinc finger, C2H2 type
      pfam01352
      Location:3473
      KRAB; KRAB box
      pfam13465
      Location:432457
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29683380..29727707
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250569.4XP_011248871.1  zinc finger protein 568 isoform X1

      See identical proteins and their annotated locations for XP_011248871.1

      UniProtKB/Swiss-Prot
      E9PYI1
      Related
      ENSMUSP00000073930.6, ENSMUST00000074322.12
      Conserved Domains (3) summary
      smart00349
      Location:3494
      KRAB; krueppel associated box
      COG5048
      Location:350665
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:589609
      ZF_C2H2; C2H2 Zn finger [structural motif]
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