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    Plekhm3 pleckstrin homology domain containing, family M, member 3 [ Mus musculus (house mouse) ]

    Gene ID: 241075, updated on 23-Jun-2021

    Summary

    Official Symbol
    Plekhm3provided by MGI
    Official Full Name
    pleckstrin homology domain containing, family M, member 3provided by MGI
    Primary source
    MGI:MGI:2443627
    See related
    Ensembl:ENSMUSG00000051344
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DAPR; Plekh; AI449570; Plekhm1l; 9430067K14Rik; A230102O09Rik
    Expression
    Ubiquitous expression in spleen adult (RPKM 4.4), cerebellum adult (RPKM 3.4) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Plekhm3 in Genome Data Viewer
    Location:
    1; 1 C2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (64828279..64995983, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (64789120..64956824, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (64835695..65003398, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene cyclin Y-like 1 Neighboring gene frizzled class receptor 5 Neighboring gene leucine rich repeat containing 15 pseudogene Neighboring gene predicted gene, 51628 Neighboring gene ribosomal protein L31, pseudogene 24 Neighboring gene predicted gene, 51627 Neighboring gene ribosomal protein L10A, pseudogene 1 Neighboring gene predicted gene, 24788

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in myoblast differentiation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    pleckstrin homology domain-containing family M member 3
    Names
    PH domain-containing family M member 3
    differentiation associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039493.1NP_001034582.1  pleckstrin homology domain-containing family M member 3

      See identical proteins and their annotated locations for NP_001034582.1

      Status: VALIDATED

      Source sequence(s)
      AC101915, BC063098
      Consensus CDS
      CCDS15009.1
      UniProtKB/Swiss-Prot
      Q8BM47
      Related
      ENSMUSP00000095320.2, ENSMUST00000097713.2
      Conserved Domains (3) summary
      cd14674
      Location:215304
      PH_PLEKHM3_1; Pleckstrin homology domain-containing family M member 3 Pleckstrin homology domain 1
      pfam13901
      Location:530727
      zf-RING_9; Putative zinc-RING and/or ribbon
      cl17171
      Location:364451
      PH-like; Pleckstrin homology-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      64828279..64995983 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495983.5XP_006496046.1  pleckstrin homology domain-containing family M member 3 isoform X2

      See identical proteins and their annotated locations for XP_006496046.1

      Conserved Domains (2) summary
      pfam13901
      Location:255452
      zf-RING_9; Putative zinc-RING and/or ribbon
      cl17171
      Location:89176
      PH-like; Pleckstrin homology-like domain
    2. XM_006495982.3XP_006496045.1  pleckstrin homology domain-containing family M member 3 isoform X1

      See identical proteins and their annotated locations for XP_006496045.1

      UniProtKB/Swiss-Prot
      Q8BM47
      Conserved Domains (3) summary
      cd14674
      Location:215304
      PH_PLEKHM3_1; Pleckstrin homology domain-containing family M member 3 Pleckstrin homology domain 1
      pfam13901
      Location:530727
      zf-RING_9; Putative zinc-RING and/or ribbon
      cl17171
      Location:364451
      PH-like; Pleckstrin homology-like domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175509.3: Suppressed sequence

      Description
      NM_175509.3: This RefSeq was permanently suppressed because it is a nonsense-mediated decay (NMD) candidate.
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