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    Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b [ Mus musculus (house mouse) ]

    Gene ID: 24099, updated on 12-Sep-2021

    Summary

    Official Symbol
    Tnfsf13bprovided by MGI
    Official Full Name
    tumor necrosis factor (ligand) superfamily, member 13bprovided by MGI
    Primary source
    MGI:MGI:1344376
    See related
    Ensembl:ENSMUSG00000031497
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BL; BAF; TAL; BAFF; BLyS; zTNF; TALL1; THANK; zTNF4; TALL-1; Tnlg7a; TNFSF20; D8Ertd387; D8Ertd387e
    Expression
    Broad expression in lung adult (RPKM 5.5), bladder adult (RPKM 3.6) and 16 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tnfsf13b in Genome Data Viewer
    Location:
    8 A1.1; 8 4.55 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (10056229..10086000)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (10006229..10036000)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (10006633..10036000)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene abhydrolase domain containing 13 Neighboring gene ligase IV, DNA, ATP-dependent Neighboring gene predicted gene 44788 Neighboring gene myosin XVI Neighboring gene predicted gene, 51560

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC124060, MGC124061

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cytokine activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables receptor ligand activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables tumor necrosis factor receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tumor necrosis factor ligand superfamily member 13B
    Names
    b cell-activating factor
    tumor necrosis factor ligand 7a

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347309.1NP_001334238.1  tumor necrosis factor ligand superfamily member 13B isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC138397, AK079180, BC106840
      Consensus CDS
      CCDS85498.1
      UniProtKB/Swiss-Prot
      Q9WU72
      UniProtKB/TrEMBL
      Q8BVA3
      Related
      ENSMUSP00000033892.9, ENSMUST00000033892.9
    2. NM_033622.2NP_296371.1  tumor necrosis factor ligand superfamily member 13B isoform 1

      See identical proteins and their annotated locations for NP_296371.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AF119383
      Consensus CDS
      CCDS22094.1
      UniProtKB/Swiss-Prot
      Q9WU72
      UniProtKB/TrEMBL
      Q3KP92
      Related
      ENSMUSP00000146694.2, ENSMUST00000207792.3
      Conserved Domains (2) summary
      cd00184
      Location:170306
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
      cl11564
      Location:81155
      GcrA; GcrA cell cycle regulator

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      10056229..10086000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006508775.4XP_006508838.1  tumor necrosis factor ligand superfamily member 13B isoform X1

      UniProtKB/TrEMBL
      A0A0U5J6R6
      Conserved Domains (1) summary
      cd00184
      Location:139275
      TNF; Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...

    RNA

    1. XR_378661.5 RNA Sequence

      Related
      ENSMUST00000208683.2
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