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    Srp54a signal recognition particle 54A [ Mus musculus (house mouse) ]

    Gene ID: 24067, updated on 23-Jun-2021

    Summary

    Official Symbol
    Srp54aprovided by MGI
    Official Full Name
    signal recognition particle 54Aprovided by MGI
    Primary source
    MGI:MGI:1346087
    See related
    Ensembl:ENSMUSG00000073079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sr; 54kD; 54kDa; Srp54
    Expression
    Ubiquitous expression in placenta adult (RPKM 34.3), bladder adult (RPKM 29.5) and 26 other tissues See more
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    Genomic context

    See Srp54a in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (55127261..55162152)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (55080476..55115367)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (56181483..56216354)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2700097O09 gene Neighboring gene predicted gene, 46350 Neighboring gene RNA polymerase II, polypeptide H Neighboring gene family with sequence similarity 177, member A Neighboring gene predicted gene 2436 Neighboring gene signal recognition particle 54B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    • Homologs of the Srp54a gene: The Srp54a gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.
    • Orthologs

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 7S RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables 7S RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables endoplasmic reticulum signal peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ribonucleoprotein complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NOT located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    signal recognition particle 54 kDa protein
    Names
    54K subunit of signal recognition particle
    NP_036029.2
    XP_030102570.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011899.4NP_036029.2  signal recognition particle 54 kDa protein

      See identical proteins and their annotated locations for NP_036029.2

      Status: VALIDATED

      Source sequence(s)
      AC157515
      Consensus CDS
      CCDS36449.1
      UniProtKB/Swiss-Prot
      P14576
      Related
      ENSMUSP00000152764.2, ENSMUST00000220578.2
      Conserved Domains (1) summary
      TIGR01425
      Location:2430
      SRP54_euk; signal recognition particle protein SRP54

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      55127261..55162152
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030246710.2XP_030102570.1  signal recognition particle 54 kDa protein isoform X1

      Conserved Domains (1) summary
      TIGR01425
      Location:4291
      SRP54_euk; signal recognition particle protein SRP54
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