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    Ccnj cyclin J [ Mus musculus (house mouse) ]

    Gene ID: 240665, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ccnjprovided by MGI
    Official Full Name
    cyclin Jprovided by MGI
    Primary source
    MGI:MGI:2443297
    See related
    Ensembl:ENSMUSG00000025010
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D430039C20Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 10.4), whole brain E14.5 (RPKM 8.0) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ccnj in Genome Data Viewer
    Location:
    19; 19 C3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (40831279..40848572)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (40905769..40923062)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene ectonucleoside triphosphate diphosphohydrolase 1 Neighboring gene predicted gene, 41846 Neighboring gene coiled-coil and C2 domain containing 2B Neighboring gene predicted gene, 33482 Neighboring gene RIKEN cDNA E030044B06 gene Neighboring gene uncharacterized LOC108168428 Neighboring gene zinc finger protein 518A Neighboring gene microRNA 8092

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118445

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172839.4NP_766427.1  cyclin-J

      See identical proteins and their annotated locations for NP_766427.1

      Status: VALIDATED

      Source sequence(s)
      AC117253
      Consensus CDS
      CCDS29806.1
      UniProtKB/Swiss-Prot
      Q3TZI6
      Related
      ENSMUSP00000025983.6, ENSMUST00000025983.12
      Conserved Domains (2) summary
      pfam02984
      Location:145295
      Cyclin_C; Cyclin, C-terminal domain
      cl00050
      Location:15109
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      40831279..40848572
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527088.2XP_006527151.1  cyclin-J isoform X2

      Conserved Domains (2) summary
      pfam02984
      Location:145284
      Cyclin_C; Cyclin, C-terminal domain
      cl00050
      Location:15109
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    2. XM_011247248.1XP_011245550.1  cyclin-J isoform X3

      See identical proteins and their annotated locations for XP_011245550.1

      UniProtKB/Swiss-Prot
      Q3TZI6
      Related
      ENSMUSP00000113712.1, ENSMUST00000120057.7
      Conserved Domains (2) summary
      pfam02984
      Location:145283
      Cyclin_C; Cyclin, C-terminal domain
      cl00050
      Location:15109
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    3. XM_017318200.1XP_017173689.1  cyclin-J isoform X1

      UniProtKB/Swiss-Prot
      Q3TZI6
      Related
      ENSMUSP00000112643.1, ENSMUST00000119316.1
      Conserved Domains (2) summary
      pfam02984
      Location:145295
      Cyclin_C; Cyclin, C-terminal domain
      cl00050
      Location:15109
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
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