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    Ccnj cyclin J [ Mus musculus (house mouse) ]

    Gene ID: 240665, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ccnjprovided by MGI
    Official Full Name
    cyclin Jprovided by MGI
    Primary source
    MGI:MGI:2443297
    See related
    Ensembl:ENSMUSG00000025010 AllianceGenome:MGI:2443297
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D430039C20Rik
    Summary
    Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. Orthologous to human CCNJ (cyclin J). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 10.4), whole brain E14.5 (RPKM 8.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ccnj in Genome Data Viewer
    Location:
    19 C3; 19 34.26 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (40819345..40837016)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (40830959..40848572)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene ectonucleoside triphosphate diphosphohydrolase 1 Neighboring gene predicted gene, 41846 Neighboring gene coiled-coil and C2 domain containing 2B Neighboring gene STARR-seq mESC enhancer starr_46135 Neighboring gene STARR-positive B cell enhancer mm9_chr19:40895901-40896202 Neighboring gene predicted gene, 33482 Neighboring gene RIKEN cDNA E030044B06 gene Neighboring gene STARR-seq mESC enhancer starr_46136 Neighboring gene predicted gene, 57494 Neighboring gene zinc finger protein 518A Neighboring gene microRNA 8092

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Clone Names

    • MGC118445

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172839.4NP_766427.1  cyclin-J

      See identical proteins and their annotated locations for NP_766427.1

      Status: VALIDATED

      Source sequence(s)
      AC117253
      Consensus CDS
      CCDS29806.1
      UniProtKB/Swiss-Prot
      Q1ED41, Q3TZI6, Q8BIY5
      Related
      ENSMUSP00000025983.7, ENSMUST00000025983.13
      Conserved Domains (2) summary
      cd20528
      Location:34140
      CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
      cd20529
      Location:145245
      CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      40819345..40837016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161597.1XP_036017490.1  cyclin-J isoform X1

      UniProtKB/Swiss-Prot
      Q1ED41, Q3TZI6, Q8BIY5
      Conserved Domains (2) summary
      cd20528
      Location:34140
      CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
      cd20529
      Location:145245
      CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family
    2. XM_030250940.1XP_030106800.1  cyclin-J isoform X2

      Conserved Domains (2) summary
      pfam00134
      Location:15109
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:145284
      Cyclin_C; Cyclin, C-terminal domain
    3. XM_036161596.1XP_036017489.1  cyclin-J isoform X1

      UniProtKB/Swiss-Prot
      Q1ED41, Q3TZI6, Q8BIY5
      Conserved Domains (2) summary
      cd20528
      Location:34140
      CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
      cd20529
      Location:145245
      CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family
    4. XM_006527088.4XP_006527151.1  cyclin-J isoform X2

      Conserved Domains (2) summary
      pfam00134
      Location:15109
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:145284
      Cyclin_C; Cyclin, C-terminal domain
    5. XM_011247248.3XP_011245550.1  cyclin-J isoform X3

      See identical proteins and their annotated locations for XP_011245550.1

      UniProtKB/Swiss-Prot
      Q3TZI6
      Conserved Domains (2) summary
      pfam00134
      Location:15109
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:145283
      Cyclin_C; Cyclin, C-terminal domain
    6. XM_017318200.3XP_017173689.1  cyclin-J isoform X1

      UniProtKB/Swiss-Prot
      Q1ED41, Q3TZI6, Q8BIY5
      Related
      ENSMUSP00000112643.2, ENSMUST00000119316.2
      Conserved Domains (2) summary
      cd20528
      Location:34140
      CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
      cd20529
      Location:145245
      CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family
    7. XM_030250941.2XP_030106801.1  cyclin-J isoform X3

      Conserved Domains (2) summary
      pfam00134
      Location:15109
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:145283
      Cyclin_C; Cyclin, C-terminal domain
    8. XM_036161595.1XP_036017488.1  cyclin-J isoform X1

      UniProtKB/Swiss-Prot
      Q1ED41, Q3TZI6, Q8BIY5
      Conserved Domains (2) summary
      cd20528
      Location:34140
      CYCLIN_CCNJ-like_rpt1; first cyclin box found in cyclin-J (CCNJ) family
      cd20529
      Location:145245
      CYCLIN_CCNJ-like_rpt2; second cyclin box found in cyclin-J (CCNJ) family