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    Kif20b kinesin family member 20B [ Mus musculus (house mouse) ]

    Gene ID: 240641, updated on 8-Jul-2021

    Summary

    Official Symbol
    Kif20bprovided by MGI
    Official Full Name
    kinesin family member 20Bprovided by MGI
    Primary source
    MGI:MGI:2444576
    See related
    Ensembl:ENSMUSG00000024795
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ma; MPP1; Mpho; 33cex; Kif20; magoo; Mphosph1; C330014J10Rik
    Expression
    Biased expression in CNS E11.5 (RPKM 8.8), liver E14 (RPKM 6.1) and 8 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Kif20b in Genome Data Viewer
    Location:
    19; 19 C1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (34899735..34953150)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (34922335..34975750)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (34996848..35050221)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22082 Neighboring gene pantothenate kinase 1 Neighboring gene microRNA 107 Neighboring gene microRNA 1950 Neighboring gene proteasome (prosome, macropain) subunit, alpha type 5 pseudogene Neighboring gene predicted gene, 50137

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • B130024C23

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables WW domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables plus-end-directed microtubule motor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in microtubule-based movement IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within neural tube closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron projection morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of mitotic cytokinetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to microtubule IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of establishment of cell polarity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of establishment of cell polarity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of establishment of protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of mitotic nuclear division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within regulation of neuron migration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in contractile ring ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    part_of kinesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in microtubule cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in midbody IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle midzone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in spindle midzone IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    kinesin-like protein KIF20B
    Names
    M-phase phosphoprotein 1
    N-6 kinesin
    kinesin-related motor interacting with PIN1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362434.1NP_001349363.1  kinesin-like protein KIF20B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC113244, BC172148
      Consensus CDS
      CCDS89382.1
      Related
      ENSMUSP00000153034.2, ENSMUST00000223907.2
      Conserved Domains (3) summary
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
      cl25574
      Location:14151701
      TOP2c; TopoisomeraseII
      cl25732
      Location:5271323
      SMC_N; RecF/RecN/SMC N terminal domain
    2. NM_183046.2NP_898867.1  kinesin-like protein KIF20B isoform 1

      See identical proteins and their annotated locations for NP_898867.1

      Status: VALIDATED

      Source sequence(s)
      AC113244, AK045067, AK135856, AK143629, AK145779, AY259532
      Consensus CDS
      CCDS37967.1
      UniProtKB/Swiss-Prot
      Q80WE4
      Related
      ENSMUSP00000084599.6, ENSMUST00000087341.7
      Conserved Domains (3) summary
      COG1196
      Location:6271492
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PTZ00108
      Location:14551741
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      34899735..34953150
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527082.4XP_006527145.1  kinesin-like protein KIF20B isoform X2

      Conserved Domains (3) summary
      COG1196
      Location:6271492
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PTZ00108
      Location:14551707
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
    2. XM_036161594.1XP_036017487.1  kinesin-like protein KIF20B isoform X3

      Conserved Domains (4) summary
      PTZ00121
      Location:10851512
      PTZ00121; MAEBL; Provisional
      PTZ00108
      Location:14151667
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      TIGR02168
      Location:5271291
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
    3. XM_006527081.4XP_006527144.1  kinesin-like protein KIF20B isoform X1

      See identical proteins and their annotated locations for XP_006527144.1

      UniProtKB/Swiss-Prot
      Q80WE4
      Conserved Domains (3) summary
      COG1196
      Location:6271492
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PTZ00108
      Location:14551741
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup
    4. XM_030250939.2XP_030106799.1  kinesin-like protein KIF20B isoform X5

      Conserved Domains (3) summary
      PTZ00108
      Location:10291315
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      TIGR02168
      Location:141937
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cl22853
      Location:189
      Motor_domain; Myosin and Kinesin motor domain
    5. XM_006527084.5XP_006527147.1  kinesin-like protein KIF20B isoform X4

      See identical proteins and their annotated locations for XP_006527147.1

      Conserved Domains (4) summary
      COG5059
      Location:2257
      KIP1; Kinesin-like protein [Cytoskeleton]
      PTZ00108
      Location:10691355
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      TIGR02168
      Location:287977
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      cl22853
      Location:189
      Motor_domain; Myosin and Kinesin motor domain
    6. XM_006527080.3XP_006527143.1  kinesin-like protein KIF20B isoform X1

      See identical proteins and their annotated locations for XP_006527143.1

      UniProtKB/Swiss-Prot
      Q80WE4
      Conserved Domains (3) summary
      COG1196
      Location:6271492
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PTZ00108
      Location:14551741
      PTZ00108; DNA topoisomerase 2-like protein; Provisional
      cd01368
      Location:58475
      KISc_KIF23_like; Kinesin motor domain, KIF23-like subgroup

    RNA

    1. XR_004940144.1 RNA Sequence

    2. XR_004940145.1 RNA Sequence

    3. XR_004940147.1 RNA Sequence

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