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    Scamp3 secretory carrier membrane protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 24045, updated on 23-Jun-2021

    Summary

    Official Symbol
    Scamp3provided by MGI
    Official Full Name
    secretory carrier membrane protein 3provided by MGI
    Primary source
    MGI:MGI:1346346
    See related
    Ensembl:ENSMUSG00000028049
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sc; Sc3
    Expression
    Ubiquitous expression in adrenal adult (RPKM 100.4), thymus adult (RPKM 60.9) and 28 other tissues See more
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    Genomic context

    See Scamp3 in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (89084698..89090077)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (89177391..89182770)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (88981407..88986692)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene pyruvate kinase liver and red blood cell Neighboring gene hyperpolarization-activated, cyclic nucleotide-gated K+ 3 Neighboring gene predicted gene, 45927 Neighboring gene CDC-like kinase 2 Neighboring gene predicted gene 16069 Neighboring gene family with sequence similarity 189, member B Neighboring gene predicted gene, 23269 Neighboring gene glucosidase, beta, acid

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Readthrough Gm45927

    Readthrough gene: Gm45927, Included gene: Clk2

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in recycling endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in trans-Golgi network membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    secretory carrier-associated membrane protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001309909.1NP_001296838.1  secretory carrier-associated membrane protein 3 isoform 1

      See identical proteins and their annotated locations for NP_001296838.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AA939832, AC161600, AK135335, AK160549, AV092991
      Consensus CDS
      CCDS84640.1
      UniProtKB/Swiss-Prot
      O35609
      UniProtKB/TrEMBL
      Q3UXS0
      Related
      ENSMUSP00000112846.2, ENSMUST00000120697.8
      Conserved Domains (1) summary
      pfam04144
      Location:135310
      SCAMP; SCAMP family
    2. NM_001309910.1NP_001296839.1  secretory carrier-associated membrane protein 3 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region and lacks an in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.
      Source sequence(s)
      AA939832, AC161600, AK160549, AV092991
      Consensus CDS
      CCDS84641.1
      UniProtKB/Swiss-Prot
      O35609
      UniProtKB/TrEMBL
      E9Q855
      Related
      ENSMUSP00000096540.5, ENSMUST00000098941.5
      Conserved Domains (1) summary
      pfam04144
      Location:134275
      SCAMP; SCAMP family
    3. NM_011886.3NP_036016.2  secretory carrier-associated membrane protein 3 isoform 2

      See identical proteins and their annotated locations for NP_036016.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AA939832, AC161600, AK160549, AV092991
      Consensus CDS
      CCDS50959.1
      UniProtKB/Swiss-Prot
      O35609
      Related
      ENSMUSP00000029684.9, ENSMUST00000029684.15
      Conserved Domains (1) summary
      pfam04144
      Location:134309
      SCAMP; SCAMP family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      89084698..89090077
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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