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    Mex3c mex3 RNA binding family member C [ Mus musculus (house mouse) ]

    Gene ID: 240396, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mex3cprovided by MGI
    Official Full Name
    mex3 RNA binding family member Cprovided by MGI
    Primary source
    MGI:MGI:2652843
    See related
    Ensembl:ENSMUSG00000037253
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rkhd; Rkhd2; BM-013; BC035207; A130001D14Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 12.1), CNS E11.5 (RPKM 9.7) and 28 other tissues See more
    Orthologs
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    Try the new Transcript table

    Genomic context

    See Mex3c in Genome Data Viewer
    Location:
    18; 18 E2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (73705710..73725649)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (73572637..73592578)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (73732359..73752232)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54025 Neighboring gene predicted gene, 32022 Neighboring gene SMAD family member 4 Neighboring gene RIKEN cDNA 4930578L24 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    RNA-binding E3 ubiquitin-protein ligase MEX3C
    Names
    MEX3C variant 1
    MEX3C variant 10
    MEX3C variant 11
    MEX3C variant 2
    MEX3C variant 3
    MEX3C variant 4
    MEX3C variant 5
    MEX3C variant 6
    MEX3C variant 9
    RING finger and KH domain-containing protein 2
    RING-type E3 ubiquitin transferase MEX3C
    RNA-binding protein MEX3C
    mex3 homolog C
    ring finger and KH domain containing 2
    NP_001034303.3
    XP_011245234.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039214.4NP_001034303.3  RNA-binding E3 ubiquitin-protein ligase MEX3C

      See identical proteins and their annotated locations for NP_001034303.3

      Status: VALIDATED

      Source sequence(s)
      BB618103, BC108422, BC125427, BY595095, CJ067036, CJ071688
      Consensus CDS
      CCDS50318.1
      UniProtKB/Swiss-Prot
      Q05A36
      Related
      ENSMUSP00000089463.5, ENSMUST00000091852.5
      Conserved Domains (3) summary
      smart00322
      Location:319384
      KH; K homology RNA-binding domain
      cd00105
      Location:226287
      KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
      pfam13920
      Location:601646
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      73705710..73725649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011246932.4XP_011245234.1  RNA-binding E3 ubiquitin-protein ligase MEX3C isoform X1

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