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    Mrps12 mitochondrial ribosomal protein S12 [ Mus musculus (house mouse) ]

    Gene ID: 24030, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mrps12provided by MGI
    Official Full Name
    mitochondrial ribosomal protein S12provided by MGI
    Primary source
    MGI:MGI:1346333
    See related
    Ensembl:ENSMUSG00000045948
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    rp; Rpm; rps12; Rpms12; AI327385
    Expression
    Ubiquitous expression in adrenal adult (RPKM 77.6), duodenum adult (RPKM 43.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Mrps12 in Genome Data Viewer
    Location:
    7; 7 B1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28439066..28441246, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28739641..28741821, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (29524660..29526800, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene F-box protein 27 Neighboring gene F-box protein 17 Neighboring gene seryl-aminoacyl-tRNA synthetase 2 Neighboring gene coiled-coil glutamate-rich protein 2 Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    28S ribosomal protein S12, mitochondrial
    Names
    MRP-S12
    MT-RPS12
    S12mt
    mitoribosomal protein s12
    ribosomal protein, mitochondrial, S12

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360250.1NP_001347179.1  28S ribosomal protein S12, mitochondrial isoform a precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1, 2, and 3 all encode the same isoform (a).
      Source sequence(s)
      AC171210, CA323119
      Consensus CDS
      CCDS21052.1
      Related
      ENSMUSP00000132443.2, ENSMUST00000171183.2
      Conserved Domains (1) summary
      cd03368
      Location:32138
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...
    2. NM_001360252.1NP_001347181.1  28S ribosomal protein S12, mitochondrial isoform a precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
      Source sequence(s)
      AC171210
      Consensus CDS
      CCDS21052.1
      Conserved Domains (1) summary
      cd03368
      Location:32138
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...
    3. NM_001360254.1NP_001347183.1  28S ribosomal protein S12, mitochondrial isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.
      Source sequence(s)
      AA606858, AC171210
      Related
      ENSMUSP00000129492.2, ENSMUST00000165004.2
    4. NM_011885.5NP_036015.1  28S ribosomal protein S12, mitochondrial isoform a precursor

      See identical proteins and their annotated locations for NP_036015.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (a).
      Source sequence(s)
      AC171210, Y11682
      Consensus CDS
      CCDS21052.1
      UniProtKB/Swiss-Prot
      O35680
      Related
      ENSMUSP00000062066.9, ENSMUST00000056078.9
      Conserved Domains (1) summary
      cd03368
      Location:32138
      Ribosomal_S12; S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28439066..28441246 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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