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    Pebp1 phosphatidylethanolamine binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 23980, updated on 31-Jan-2019

    Summary

    Official Symbol
    Pebp1provided by MGI
    Official Full Name
    phosphatidylethanolamine binding protein 1provided by MGI
    Primary source
    MGI:MGI:1344408
    See related
    Ensembl:ENSMUSG00000032959
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pbp; HCNP; Pbp1; Pbpr; Rkip
    Expression
    Broad expression in testis adult (RPKM 1168.4), adrenal adult (RPKM 808.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Pebp1 in Genome Data Viewer
    Location:
    5 F; 5 56.88 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (117282651..117287564, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (117732660..117737573, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene suppressor of defective silencing 3 homolog (S. cerevisiae) Neighboring gene TAO kinase 3 Neighboring gene predicted gene 3786 Neighboring gene V-set and immunoglobulin domain containing 10 Neighboring gene 60S ribosomal protein L27a pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102065, MGC103131

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    mitogen-activated protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitogen-activated protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    peptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    receptor serine/threonine kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    aging IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hippocampus development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of peptidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of acetylcholine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of acetylcholine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cAMP-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cAMP-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of mitotic nuclear division ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of neurotransmitter levels IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of neurotransmitter levels ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of the force of heart contraction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of the force of heart contraction ISO
    Inferred from Sequence Orthology
    more info
     
    response to activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to cAMP IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to calcium ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to corticosterone IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to ethanol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to heat IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to organonitrogen compound IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to oxidative stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to toxic substance IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to wounding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sperm capacitation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sperm capacitation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    apical part of cell IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    axon terminus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    axon terminus ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath HDA PubMed 
    myelin sheath IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    rough endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    synaptic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    phosphatidylethanolamine-binding protein 1
    Names
    HCNPpp
    PEBP-1
    Raf-1 inhibitor protein
    Raf-1 kinase inhibitor protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018858.2NP_061346.2  phosphatidylethanolamine-binding protein 1

      See identical proteins and their annotated locations for NP_061346.2

      Status: PROVISIONAL

      Source sequence(s)
      BC083063
      Consensus CDS
      CCDS39234.1
      UniProtKB/Swiss-Prot
      P70296
      UniProtKB/TrEMBL
      Q5EBQ2
      Related
      ENSMUSP00000048425.6, ENSMUST00000036951.12
      Conserved Domains (1) summary
      cd00866
      Location:25171
      PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      117282651..117287564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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