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    Cdh24 cadherin-like 24 [ Mus musculus (house mouse) ]

    Gene ID: 239096, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cdh24provided by MGI
    Official Full Name
    cadherin-like 24provided by MGI
    Primary source
    MGI:MGI:1928330
    See related
    Ensembl:ENSMUSG00000059674
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700040A22Rik
    Expression
    Biased expression in thymus adult (RPKM 40.1), whole brain E14.5 (RPKM 18.9) and 14 other tissues See more
    Orthologs

    Genomic context

    See Cdh24 in Genome Data Viewer
    Location:
    14; 14 C2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (54631992..54642067, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (55250829..55260201, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene proteasome (prosome, macropain) subunit, beta type 5 Neighboring gene microRNA 686 Neighboring gene proteasome (prosome, macropain) subunit, beta type, 11 Neighboring gene microRNA 6948 Neighboring gene apoptotic chromatin condensation inducer 1 Neighboring gene RIKEN cDNA 4930579G18 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC67331

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    alpha-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    cadherin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeletal protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    delta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein homodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    adherens junction organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    cell-cell adhesion mediated by cadherin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    homophilic cell adhesion via plasma membrane adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cadherin-24
    Names
    EY-cadherin

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199470.2NP_955764.1  cadherin-24 precursor

      See identical proteins and their annotated locations for NP_955764.1

      Status: VALIDATED

      Source sequence(s)
      BC057373, CJ087875
      Consensus CDS
      CCDS36923.1
      UniProtKB/Swiss-Prot
      Q6PFX6
      Related
      ENSMUSP00000066005.6, ENSMUST00000067784.7
      Conserved Domains (4) summary
      cd11304
      Location:378475
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:70148
      CA; Cadherin repeats
      pfam01049
      Location:633774
      Cadherin_C; Cadherin cytoplasmic region
      cl09101
      Location:483577
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      54631992..54642067 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518975.3XP_006519038.1  cadherin-24 isoform X1

      Conserved Domains (2) summary
      cd11304
      Location:154255
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:70148
      CA; Cadherin repeats
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