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    Cdh24 cadherin-like 24 [ Mus musculus (house mouse) ]

    Gene ID: 239096, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cdh24provided by MGI
    Official Full Name
    cadherin-like 24provided by MGI
    Primary source
    MGI:MGI:1928330
    See related
    Ensembl:ENSMUSG00000059674
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EY-cadh; 1700040A22Rik
    Expression
    Biased expression in thymus adult (RPKM 40.1), whole brain E14.5 (RPKM 18.9) and 14 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cdh24 in Genome Data Viewer
    Location:
    14; 14 C2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (54868688..54879079, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (54631231..54642067, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (55250829..55260201, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene proteasome (prosome, macropain) subunit, beta type 5 Neighboring gene microRNA 686 Neighboring gene proteasome (prosome, macropain) subunit, beta type, 11 Neighboring gene microRNA 6948 Neighboring gene apoptotic chromatin condensation inducer 1 Neighboring gene RIKEN cDNA 4930579G18 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Clone Names

    • MGC67331

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables alpha-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables cadherin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables delta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in adherens junction organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell-cell adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell adhesion via plasma-membrane adhesion molecules IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in cell-cell junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in multicellular organism development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of catenin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cadherin-24
    Names
    EY-cadherin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199470.2NP_955764.1  cadherin-24 precursor

      See identical proteins and their annotated locations for NP_955764.1

      Status: VALIDATED

      Source sequence(s)
      BC057373, CJ087875
      Consensus CDS
      CCDS36923.1
      UniProtKB/Swiss-Prot
      Q6PFX6
      Related
      ENSMUSP00000066005.7, ENSMUST00000067784.8
      Conserved Domains (4) summary
      cd11304
      Location:378475
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:70148
      CA; Cadherin repeats
      cl29226
      Location:485577
      Cadherin; Cadherin domain
      pfam01049
      Location:625776
      Cadherin_C; Cadherin cytoplasmic region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      54868688..54879079 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030247793.2XP_030103653.1  cadherin-24 isoform X1

      Conserved Domains (4) summary
      cd11304
      Location:378475
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:70148
      CA; Cadherin repeats
      cl29226
      Location:485577
      Cadherin; Cadherin domain
      pfam01049
      Location:625776
      Cadherin_C; Cadherin cytoplasmic region
    2. XM_030247794.2XP_030103654.1  cadherin-24 isoform X2

      Conserved Domains (2) summary
      cd11304
      Location:154255
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:70148
      CA; Cadherin repeats
    3. XM_006518975.5XP_006519038.1  cadherin-24 isoform X3

      Conserved Domains (2) summary
      cd11304
      Location:154255
      Cadherin_repeat; Cadherin tandem repeat domain
      smart00112
      Location:70148
      CA; Cadherin repeats
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