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    Hs2st1 heparan sulfate 2-O-sulfotransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 23908, updated on 28-Aug-2021

    Summary

    Official Symbol
    Hs2st1provided by MGI
    Official Full Name
    heparan sulfate 2-O-sulfotransferase 1provided by MGI
    Primary source
    MGI:MGI:1346049
    See related
    Ensembl:ENSMUSG00000040151
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hs2; 2OST; Hs2st; AW214369; mKIAA0448
    Expression
    Ubiquitous expression in lung adult (RPKM 8.3), whole brain E14.5 (RPKM 6.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Hs2st1 in Genome Data Viewer
    Location:
    3; 3 H2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (144135462..144275977, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (144429701..144570216, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (144094071..144233180, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54186 Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene predicted gene 43560 Neighboring gene predicted gene, 46829 Neighboring gene selenoprotein F Neighboring gene ribosomal protein L9, pseudogene 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heparan sulfate 2-O-sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables heparan sulfate 2-O-sulfotransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    heparan sulfate 2-O-sulfotransferase 1
    Names
    2-O-sulfotransferase
    NP_001342163.1
    NP_035958.3
    XP_006501513.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355234.1NP_001342163.1  heparan sulfate 2-O-sulfotransferase 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC123880, AC159976, BC059008
      Conserved Domains (1) summary
      pfam03567
      Location:76327
      Sulfotransfer_2; Sulfotransferase family
    2. NM_011828.4NP_035958.3  heparan sulfate 2-O-sulfotransferase 1 isoform 2

      See identical proteins and their annotated locations for NP_035958.3

      Status: VALIDATED

      Source sequence(s)
      AC123880, AC159976, BC059008
      Consensus CDS
      CCDS17883.1
      UniProtKB/Swiss-Prot
      Q8R3H7
      Related
      ENSMUSP00000043066.8, ENSMUST00000043325.9
      Conserved Domains (1) summary
      pfam03567
      Location:76326
      Sulfotransfer_2; Sulfotransferase family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      144135462..144275977 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501450.5XP_006501513.1  heparan sulfate 2-O-sulfotransferase 1 isoform X1

      Conserved Domains (1) summary
      pfam03567
      Location:18269
      Sulfotransfer_2; Sulfotransferase family
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