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    Dmtf1 cyclin D binding myb-like transcription factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 23857, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dmtf1provided by MGI
    Official Full Name
    cyclin D binding myb-like transcription factor 1provided by MGI
    Primary source
    MGI:MGI:1344415
    See related
    Ensembl:ENSMUSG00000042508
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dimp; Dmp1
    Expression
    Ubiquitous expression in CNS E14 (RPKM 13.2), CNS E18 (RPKM 12.2) and 24 other tissues See more
    Orthologs

    Genomic context

    See Dmtf1 in Genome Data Viewer
    Location:
    5; 5 A1
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (9118868..9161776, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (9118868..9161776, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40264 Neighboring gene predicted gene, 31449 Neighboring gene transmembrane protein 243, mitochondrial Neighboring gene predicted gene, 46901 Neighboring gene RIKEN cDNA 9330182L06 gene Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14B pseudogene Neighboring gene microRNA 879

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cyclin-D-binding Myb-like transcription factor 1
    Names
    D-interacting myb-like protein
    cyclin D binding myb-like transcription factor 1D-interacting myb-like protein
    cyclin-D-interacting Myb-like protein 1
    mDmp1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110327.1NP_001103797.1  cyclin-D-binding Myb-like transcription factor 1 isoform 2

      See identical proteins and their annotated locations for NP_001103797.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AK160595, BF466048, BM243709, BY247901
      Consensus CDS
      CCDS51412.1
      UniProtKB/Swiss-Prot
      Q8CE22
      Related
      ENSMUSP00000092627.4, ENSMUST00000095017.10
      Conserved Domains (4) summary
      smart00717
      Location:274330
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:338388
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:274329
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:228284
      Myb_DNA-bind_6; Myb-like DNA-binding domain
    2. NM_011806.3NP_035936.3  cyclin-D-binding Myb-like transcription factor 1 isoform 1

      See identical proteins and their annotated locations for NP_035936.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK029147, BC060109, BF466048, BY247901
      Consensus CDS
      CCDS19088.1
      UniProtKB/Swiss-Prot
      Q8CE22
      Related
      ENSMUSP00000071815.5, ENSMUST00000071921.12
      Conserved Domains (4) summary
      smart00717
      Location:274330
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:338388
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:274329
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:228284
      Myb_DNA-bind_6; Myb-like DNA-binding domain

    RNA

    1. NR_152858.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107763, AC158121
    2. NR_152859.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107763, AC158121
    3. NR_152860.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107763, AC158121, AK039563
    4. NR_152861.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC107763, AC158121, AK046201

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      9118868..9161776 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011240669.1XP_011238971.1  cyclin-D-binding Myb-like transcription factor 1 isoform X3

      Conserved Domains (4) summary
      smart00717
      Location:274330
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:338388
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:274329
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:228284
      Myb_DNA-bind_6; Myb-like DNA-binding domain
    2. XM_006503572.3XP_006503635.1  cyclin-D-binding Myb-like transcription factor 1 isoform X2

      Related
      ENSMUSP00000139361.1, ENSMUST00000183973.7
      Conserved Domains (4) summary
      smart00717
      Location:233289
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:297347
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:233288
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:187243
      Myb_DNA-bind_6; Myb-like DNA-binding domain
    3. XM_017320878.1XP_017176367.1  cyclin-D-binding Myb-like transcription factor 1 isoform X2

      Conserved Domains (4) summary
      smart00717
      Location:233289
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:297347
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:233288
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:187243
      Myb_DNA-bind_6; Myb-like DNA-binding domain
    4. XM_011240668.2XP_011238970.1  cyclin-D-binding Myb-like transcription factor 1 isoform X1

      See identical proteins and their annotated locations for XP_011238970.1

      UniProtKB/Swiss-Prot
      Q8CE22
      Conserved Domains (4) summary
      smart00717
      Location:274330
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:338388
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:274329
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam13921
      Location:228284
      Myb_DNA-bind_6; Myb-like DNA-binding domain
    5. XM_006503574.1XP_006503637.1  cyclin-D-binding Myb-like transcription factor 1 isoform X4

      Conserved Domains (3) summary
      smart00717
      Location:864
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:72122
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:863
      Myb_DNA-binding; Myb-like DNA-binding domain

    RNA

    1. XR_001784691.1 RNA Sequence

      Related
      ENSMUST00000183448.7
    2. XR_001784690.1 RNA Sequence

      Related
      ENSMUST00000184888.7
    3. XR_001784692.1 RNA Sequence

      Related
      ENSMUST00000184620.7
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