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    Arid4a AT rich interactive domain 4A (RBP1-like) [ Mus musculus (house mouse) ]

    Gene ID: 238247, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arid4aprovided by MGI
    Official Full Name
    AT rich interactive domain 4A (RBP1-like)provided by MGI
    Primary source
    MGI:MGI:2444354
    See related
    Ensembl:ENSMUSG00000048118
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rbbp1; A630009N03; A630067N03Rik
    Expression
    Ubiquitous expression in bladder adult (RPKM 3.7), frontal lobe adult (RPKM 3.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Arid4a in Genome Data Viewer
    Location:
    12; 12 C2
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (71015967..71099351)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (72116954..72200338)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA lysine 17 (anticodon CTT) Neighboring gene proteasome (prosome, macropain) subunit, alpha type 3 Neighboring gene RIKEN cDNA 3110056K07 gene Neighboring gene translocase of outer mitochondrial membrane 20-like Neighboring gene predicted gene, 32906 Neighboring gene translocase of inner mitochondrial membrane 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription regulatory region DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    erythrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    establishment of Sertoli cell barrier IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    histone H3-K4 trimethylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone H3-K9 trimethylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    histone H3-K9 trimethylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    histone H4-K20 trimethylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    histone H4-K20 trimethylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of gene expression by genetic imprinting IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spermatogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    transcriptional repressor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    AT-rich interactive domain-containing protein 4A
    Names
    ARID domain-containing protein 4A
    AT rich interactive domain 4A (Rbp1 like)
    retinoblastoma-binding protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081195.1NP_001074664.1  AT-rich interactive domain-containing protein 4A

      See identical proteins and their annotated locations for NP_001074664.1

      Status: VALIDATED

      Source sequence(s)
      AC112794, AC132325
      Consensus CDS
      CCDS36471.1
      UniProtKB/TrEMBL
      F8VPQ2
      Related
      ENSMUSP00000035512.5, ENSMUST00000046305.11
      Conserved Domains (5) summary
      smart00501
      Location:312401
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00333
      Location:58113
      TUDOR; Tudor domain
      pfam03528
      Location:778937
      Rabaptin; Rabaptin
      pfam08169
      Location:175261
      RBB1NT; RBB1NT (NUC162) domain
      pfam11717
      Location:578632
      Tudor-knot; RNA binding activity-knot of a chromodomain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      71015967..71099351
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244105.1XP_011242407.1  AT-rich interactive domain-containing protein 4A isoform X3

      Conserved Domains (4) summary
      smart00501
      Location:312401
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00333
      Location:58113
      TUDOR; Tudor domain
      pfam08169
      Location:171261
      RBB1NT; RBB1NT (NUC162) domain
      pfam11717
      Location:578632
      Tudor-knot; RNA binding activity-knot of a chromodomain
    2. XM_017315057.1XP_017170546.1  AT-rich interactive domain-containing protein 4A isoform X1

      UniProtKB/TrEMBL
      F8VPQ2
      Conserved Domains (5) summary
      smart00501
      Location:312401
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      smart00333
      Location:58113
      TUDOR; Tudor domain
      pfam03528
      Location:778937
      Rabaptin; Rabaptin
      pfam08169
      Location:175261
      RBB1NT; RBB1NT (NUC162) domain
      pfam11717
      Location:578632
      Tudor-knot; RNA binding activity-knot of a chromodomain
    3. XM_006515834.3XP_006515897.1  AT-rich interactive domain-containing protein 4A isoform X2

      Conserved Domains (2) summary
      smart00501
      Location:179
      BRIGHT; BRIGHT, ARID (A/T-rich interaction domain) domain
      pfam11717
      Location:256310
      Tudor-knot; RNA binding activity-knot of a chromodomain
    4. XM_006515835.1XP_006515898.1  AT-rich interactive domain-containing protein 4A isoform X5

      Conserved Domains (1) summary
      pfam11717
      Location:129
      Tudor-knot; RNA binding activity-knot of a chromodomain
    5. XM_011244106.2XP_011242408.1  AT-rich interactive domain-containing protein 4A isoform X4

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