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    Cdk17 cyclin-dependent kinase 17 [ Mus musculus (house mouse) ]

    Gene ID: 237459, updated on 10-Aug-2021

    Summary

    Official Symbol
    Cdk17provided by MGI
    Official Full Name
    cyclin-dependent kinase 17provided by MGI
    Primary source
    MGI:MGI:97517
    See related
    Ensembl:ENSMUSG00000020015
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pctk; Pctk2; 6430598J10Rik
    Expression
    Broad expression in frontal lobe adult (RPKM 15.4), cortex adult (RPKM 13.0) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Cdk17 in Genome Data Viewer
    Location:
    10; 10 C2
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (92996492..93086956)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (93160876..93251094)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (92623621..92704087)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40740 Neighboring gene predicted gene, 40741 Neighboring gene microRNA 1931 Neighboring gene ELK3, member of ETS oncogene family Neighboring gene predicted gene, 32604 Neighboring gene predicted gene, 32551

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC25109

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cyclin-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of transcription involved in G1/S transition of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cyclin-dependent kinase 17
    Names
    PCTAIRE-motif protein kinase 2
    Pctaire2
    cell division protein kinase 17
    serine/threonine-protein kinase PCTAIRE-2
    NP_666351.2
    XP_006513689.1
    XP_006513690.1
    XP_011241749.1
    XP_030100944.1
    XP_030100945.1
    XP_036011671.1
    XP_036011672.1
    XP_036011673.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146239.2NP_666351.2  cyclin-dependent kinase 17

      See identical proteins and their annotated locations for NP_666351.2

      Status: VALIDATED

      Source sequence(s)
      BB085519, BC064815, BQ442862, BU841444, BY130550, CD350146, CJ117086, CX242491, DV646930
      Consensus CDS
      CCDS48670.1
      UniProtKB/Swiss-Prot
      Q8K0D0
      Related
      ENSMUSP00000070355.8, ENSMUST00000069965.9
      Conserved Domains (1) summary
      cd07872
      Location:185493
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      92996492..93086956
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155778.1XP_036011671.1  cyclin-dependent kinase 17 isoform X4

      Related
      ENSMUSP00000150873.2, ENSMUST00000215286.2
      Conserved Domains (1) summary
      cd07872
      Location:185493
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    2. XM_030245085.1XP_030100945.1  cyclin-dependent kinase 17 isoform X5

      Conserved Domains (1) summary
      cd07872
      Location:101409
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    3. XM_011243447.3XP_011241749.1  cyclin-dependent kinase 17 isoform X3

      See identical proteins and their annotated locations for XP_011241749.1

      UniProtKB/Swiss-Prot
      Q8K0D0
      Conserved Domains (1) summary
      cd07872
      Location:185493
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    4. XM_006513627.4XP_006513690.1  cyclin-dependent kinase 17 isoform X3

      See identical proteins and their annotated locations for XP_006513690.1

      UniProtKB/Swiss-Prot
      Q8K0D0
      Conserved Domains (1) summary
      cd07872
      Location:185493
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    5. XM_030245084.2XP_030100944.1  cyclin-dependent kinase 17 isoform X2

      Conserved Domains (1) summary
      cd07872
      Location:201509
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    6. XM_006513626.3XP_006513689.1  cyclin-dependent kinase 17 isoform X1

      Conserved Domains (1) summary
      cd07872
      Location:201509
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    7. XM_036155780.1XP_036011673.1  cyclin-dependent kinase 17 isoform X6

      Conserved Domains (1) summary
      cd07872
      Location:101409
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase
    8. XM_036155779.1XP_036011672.1  cyclin-dependent kinase 17 isoform X5

      Conserved Domains (1) summary
      cd07872
      Location:101409
      STKc_PCTAIRE2; Catalytic domain of the Serine/Threonine Kinase, PCTAIRE-2 kinase

    RNA

    1. XR_003948686.1 RNA Sequence

    2. XR_003948687.2 RNA Sequence

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