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    Klhl15 kelch-like 15 [ Mus musculus (house mouse) ]

    Gene ID: 236904, updated on 23-Jun-2021

    Summary

    Official Symbol
    Klhl15provided by MGI
    Official Full Name
    kelch-like 15provided by MGI
    Primary source
    MGI:MGI:1923400
    See related
    Ensembl:ENSMUSG00000043929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6330500C13Rik
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Klhl15 in Genome Data Viewer
    Location:
    X; X C3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (93275884..93321330)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (94232278..94277724)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (91480269..91518854)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene zinc finger protein X-linked Neighboring gene predicted gene, 46691 Neighboring gene eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked Neighboring gene microRNA 7673 Neighboring gene predicted gene 5400 Neighboring gene predicted gene 14826

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • MGC47138

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039059.1NP_001034148.1  kelch-like protein 15 isoform c

      See identical proteins and their annotated locations for NP_001034148.1

      Status: VALIDATED

      Source sequence(s)
      AK081546, AK165342, AK169500
      Consensus CDS
      CCDS41062.1
      UniProtKB/Swiss-Prot
      A2AAX3
      Related
      ENSMUSP00000109541.2, ENSMUST00000113908.8
      Conserved Domains (2) summary
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    2. NM_001039060.1NP_001034149.1  kelch-like protein 15 isoform b

      See identical proteins and their annotated locations for NP_001034149.1

      Status: VALIDATED

      Source sequence(s)
      AK081546, AK165342, AK169500
      Consensus CDS
      CCDS30279.1
      UniProtKB/Swiss-Prot
      A2AAX3
      Related
      ENSMUSP00000094097.4, ENSMUST00000096369.10
      Conserved Domains (3) summary
      smart00225
      Location:32128
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:133235
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:21125
      BTB; BTB/POZ domain
    3. NM_001039061.1NP_001034150.1  kelch-like protein 15 isoform a

      See identical proteins and their annotated locations for NP_001034150.1

      Status: VALIDATED

      Source sequence(s)
      AK078112, AK081546, AK133055, AL646049
      Consensus CDS
      CCDS30278.1
      UniProtKB/Swiss-Prot
      A2AAX3
      Related
      ENSMUSP00000109549.4, ENSMUST00000113916.10
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    4. NM_153165.2NP_694805.1  kelch-like protein 15 isoform c

      See identical proteins and their annotated locations for NP_694805.1

      Status: VALIDATED

      Source sequence(s)
      AK081546, AK165342, AK169500
      Consensus CDS
      CCDS41062.1
      UniProtKB/Swiss-Prot
      A2AAX3
      Related
      ENSMUSP00000109544.3, ENSMUST00000113911.9
      Conserved Domains (2) summary
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      93275884..93321330
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527986.4XP_006528049.1  kelch-like protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006528049.1

      UniProtKB/Swiss-Prot
      A2AAX3
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    2. XM_006527989.4XP_006528052.1  kelch-like protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006528052.1

      UniProtKB/Swiss-Prot
      A2AAX3
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    3. XM_006527991.5XP_006528054.1  kelch-like protein 15 isoform X2

      See identical proteins and their annotated locations for XP_006528054.1

      UniProtKB/Swiss-Prot
      A2AAX3
      Conserved Domains (2) summary
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    4. XM_030251323.2XP_030107183.1  kelch-like protein 15 isoform X2

      Conserved Domains (2) summary
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    5. XM_030251322.2XP_030107182.1  kelch-like protein 15 isoform X1

      Related
      ENSMUSP00000129734.2, ENSMUST00000170594.8
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    6. XM_006527990.5XP_006528053.1  kelch-like protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006528053.1

      UniProtKB/Swiss-Prot
      A2AAX3
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    7. XM_006527987.4XP_006528050.1  kelch-like protein 15 isoform X1

      See identical proteins and their annotated locations for XP_006528050.1

      UniProtKB/Swiss-Prot
      A2AAX3
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    8. XM_011247581.1XP_011245883.1  kelch-like protein 15 isoform X1

      See identical proteins and their annotated locations for XP_011245883.1

      UniProtKB/Swiss-Prot
      A2AAX3
      Related
      ENSMUSP00000109548.2, ENSMUST00000113915.2
      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
    9. XM_036161925.1XP_036017818.1  kelch-like protein 15 isoform X1

      Conserved Domains (4) summary
      PHA03098
      Location:33576
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:417474
      Kelch; KELCH repeat [structural motif]
      cd18244
      Location:1137
      BTB_POZ_KLHL15; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 15 (KLHL15)
      cd18454
      Location:128235
      BACK_KLHL15; BACK (BTB and C-terminal Kelch) domain found in Kelch-like protein 15 (KLHL15)
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