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    Mmgt1 membrane magnesium transporter 1 [ Mus musculus (house mouse) ]

    Gene ID: 236792, updated on 26-Sep-2022

    Summary

    Official Symbol
    Mmgt1provided by MGI
    Official Full Name
    membrane magnesium transporter 1provided by MGI
    Primary source
    MGI:MGI:2384305
    See related
    Ensembl:ENSMUSG00000061273 AllianceGenome:MGI:2384305
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Emc5; Tmem32; Mir5116; mir-5116; 9630048L06Rik
    Summary
    Enables cobalt ion transmembrane transporter activity; ferrous iron transmembrane transporter activity; and magnesium ion transmembrane transporter activity. Acts upstream of or within metal ion transport. Located in Golgi apparatus; early endosome; and plasma membrane. Is expressed in several structures, including alimentary system; axial musculature; central nervous system; ganglia; and sensory organ. Orthologous to human MMGT1 (membrane magnesium transporter 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 13.0), CNS E18 (RPKM 12.2) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Mmgt1 in Genome Data Viewer
    Location:
    X; X A5
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (55630872..55643304, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (56585512..56597944, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 6 like Neighboring gene predicted gene 648 Neighboring gene microRNA 5116 Neighboring gene predicted gene, 36239 Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC40705

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of EMC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of EMC complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane IC
    Inferred by Curator
    more info
    PubMed 
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ER membrane protein complex subunit 5
    Names
    transmembrane protein 32

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146234.4NP_666346.1  ER membrane protein complex subunit 5 precursor

      See identical proteins and their annotated locations for NP_666346.1

      Status: VALIDATED

      Source sequence(s)
      AC048362
      Consensus CDS
      CCDS30147.1
      UniProtKB/Swiss-Prot
      A7UH87, Q8K273
      UniProtKB/TrEMBL
      A0A6P5P8A0, A0A8C6II73
      Related
      ENSMUSP00000051621.3, ENSMUST00000059899.3
      Conserved Domains (1) summary
      pfam10270
      Location:2961
      MMgT; Membrane magnesium transporter

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      55630872..55643304 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)