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    Zfp445 zinc finger protein 445 [ Mus musculus (house mouse) ]

    Gene ID: 235682, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp445provided by MGI
    Official Full Name
    zinc finger protein 445provided by MGI
    Primary source
    MGI:MGI:2143340
    See related
    Ensembl:ENSMUSG00000047036
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ZNF16; ZNF168; Znf445; mszf29; mszf50; AW610627
    Expression
    Broad expression in CNS E18 (RPKM 31.5), CNS E14 (RPKM 28.7) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp445 in Genome Data Viewer
    Location:
    9; 9 F4
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (122677975..122715916, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (122848910..122886851, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (122758028..122775124, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene testis and ovary specific PAZ domain containing 1 Neighboring gene T cell activation inhibitor, mitochondrial Neighboring gene predicted gene, 35549 Neighboring gene zinc finger with KRAB and SCAN domains 7 Neighboring gene zinc finger protein 660 Neighboring gene zinc finger protein 105

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables double-stranded methylated DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables double-stranded methylated DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001359934.1NP_001346863.1  zinc finger protein 445 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC125374
      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001359935.1NP_001346864.1  zinc finger protein 445 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC125374
      Consensus CDS
      CCDS23648.1
      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:219277
      KRAB; krueppel associated box
      COG5048
      Location:554983
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:636656
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_173364.5NP_775540.4  zinc finger protein 445 isoform 1

      See identical proteins and their annotated locations for NP_775540.4

      Status: VALIDATED

      Source sequence(s)
      AC125374, AY341877, BY264100, CD559799
      Consensus CDS
      CCDS23648.1
      UniProtKB/Swiss-Prot
      Q8R2V3
      UniProtKB/TrEMBL
      Q8CBF5
      Related
      ENSMUSP00000151198.2, ENSMUST00000216063.2
      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:219277
      KRAB; krueppel associated box
      COG5048
      Location:554983
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:636656
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      122677975..122715916 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512121.3XP_006512184.1  zinc finger protein 445 isoform X1

      See identical proteins and their annotated locations for XP_006512184.1

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_036154922.1XP_036010815.1  zinc finger protein 445 isoform X2

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:219277
      KRAB; krueppel associated box
      COG5048
      Location:554983
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:636656
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_006512119.4XP_006512182.1  zinc finger protein 445 isoform X1

      See identical proteins and their annotated locations for XP_006512182.1

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. XM_006512120.4XP_006512183.1  zinc finger protein 445 isoform X1

      See identical proteins and their annotated locations for XP_006512183.1

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. XM_036154921.1XP_036010814.1  zinc finger protein 445 isoform X2

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:219277
      KRAB; krueppel associated box
      COG5048
      Location:554983
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:636656
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. XM_006512118.3XP_006512181.1  zinc finger protein 445 isoform X1

      See identical proteins and their annotated locations for XP_006512181.1

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    7. XM_036154923.1XP_036010816.1  zinc finger protein 445 isoform X2

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:219277
      KRAB; krueppel associated box
      COG5048
      Location:554983
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:636656
      ZF_C2H2; C2H2 Zn finger [structural motif]
    8. XM_011242971.1XP_011241273.1  zinc finger protein 445 isoform X1

      See identical proteins and their annotated locations for XP_011241273.1

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    9. XM_006512122.3XP_006512185.1  zinc finger protein 445 isoform X1

      See identical proteins and their annotated locations for XP_006512185.1

      Conserved Domains (4) summary
      smart00431
      Location:48160
      SCAN; leucine rich region
      smart00349
      Location:231289
      KRAB; krueppel associated box
      COG5048
      Location:566995
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:648668
      ZF_C2H2; C2H2 Zn finger [structural motif]
    10. XM_036154924.1XP_036010817.1  zinc finger protein 445 isoform X3

      Conserved Domains (2) summary
      COG5048
      Location:199628
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:281301
      ZF_C2H2; C2H2 Zn finger [structural motif]
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