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    Atrip ATR interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 235610, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atripprovided by MGI
    Official Full Name
    ATR interacting proteinprovided by MGI
    Primary source
    MGI:MGI:1925349
    See related
    Ensembl:ENSMUSG00000025646
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6620401K05Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 11.5), thymus adult (RPKM 7.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atrip in Genome Data Viewer
    Location:
    9; 9 F2
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (109059747..109074530, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (108962261..108976638, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene shisa family member 5 Neighboring gene three prime repair exonuclease 1 Neighboring gene translational machinery associated 7 Neighboring gene coiled-coil domain containing 51

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Readthrough Atrip-trex1

    Readthrough gene: Atrip-trex1, Included gene: Trex1

    Homology

    Clone Names

    • MGC90531

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    K63-linked polyubiquitin modification-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA damage checkpoint IEA
    Inferred from Electronic Annotation
    more info
     
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ATR-interacting protein
    Names
    ATM and Rad3 related interacting protein
    NP_766362.2
    XP_006512135.1
    XP_011241262.1
    XP_017168839.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172774.3NP_766362.2  ATR-interacting protein

      See identical proteins and their annotated locations for NP_766362.2

      Status: VALIDATED

      Source sequence(s)
      AC140383, AK031257, BB649616
      Consensus CDS
      CCDS23545.1
      UniProtKB/Swiss-Prot
      Q8BMG1
      Related
      ENSMUSP00000044831.2, ENSMUST00000045011.8
      Conserved Domains (1) summary
      cl09111
      Location:117205
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      109059747..109074530 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242960.2XP_011241262.1  ATR-interacting protein isoform X2

      Conserved Domains (1) summary
      pfam13863
      Location:182
      DUF4200; Domain of unknown function (DUF4200)
    2. XM_006512072.2XP_006512135.1  ATR-interacting protein isoform X1

      Conserved Domains (1) summary
      cl09111
      Location:40128
      Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
    3. XM_017313350.1XP_017168839.1  ATR-interacting protein isoform X3

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