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    Rnf214 ring finger protein 214 [ Mus musculus (house mouse) ]

    Gene ID: 235315, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rnf214provided by MGI
    Official Full Name
    ring finger protein 214provided by MGI
    Primary source
    MGI:MGI:2444451
    See related
    Ensembl:ENSMUSG00000042790
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D130054N24Rik
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 13.2), cerebellum adult (RPKM 12.0) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rnf214 in Genome Data Viewer
    Location:
    9; 9 A5.2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (45768067..45818209, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (45856769..45906911, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (45671774..45714960, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene centrosomal protein 164 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene beta-site APP cleaving enzyme 1 Neighboring gene predicted gene, 24646 Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene transgelin Neighboring gene microRNA 7087 Neighboring gene SID1 transmembrane family, member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310839.2NP_001297768.1  RING finger protein 214 isoform 2

      See identical proteins and their annotated locations for NP_001297768.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
      Source sequence(s)
      AK028768, AK032376, AK051527, AK136229, BY785775, CJ286540
      Consensus CDS
      CCDS80987.1
      UniProtKB/Swiss-Prot
      Q8BFU3
      Related
      ENSMUSP00000124296.2, ENSMUST00000161187.8
      Conserved Domains (1) summary
      cd16477
      Location:466510
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    2. NM_001310840.2NP_001297769.1  RING finger protein 214 isoform 3

      See identical proteins and their annotated locations for NP_001297769.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR, uses an alternate in-frame splice site in the 5' coding region, and contains an alternate in-frame exon in the 3' coding region compared to variant 1. It encodes isoform 3, which is shorter than isoform 1.
      Source sequence(s)
      AK030208, AK032376, AK136229, BY785775, CJ286540
      Consensus CDS
      CCDS80988.1
      UniProtKB/Swiss-Prot
      Q8BFU3
      Related
      ENSMUSP00000123995.2, ENSMUST00000161203.8
      Conserved Domains (1) summary
      cd16477
      Location:501545
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    3. NM_001361112.1NP_001348041.1  RING finger protein 214 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AK030208, AK136229, BY785775, CJ286540
      Consensus CDS
      CCDS23136.1
      Related
      ENSMUSP00000123754.2, ENSMUST00000160699.9
      Conserved Domains (1) summary
      cd16477
      Location:621665
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    4. NM_001361113.1NP_001348042.1  RING finger protein 214 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AK028768, AK136229, BY785775, CJ286540
      Conserved Domains (1) summary
      cd16477
      Location:566610
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    5. NM_001361114.1NP_001348043.1  RING finger protein 214 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC126804
      Consensus CDS
      CCDS80987.1
      Conserved Domains (1) summary
      cd16477
      Location:466510
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    6. NM_178709.5NP_848824.1  RING finger protein 214 isoform 1

      See identical proteins and their annotated locations for NP_848824.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC126804
      Consensus CDS
      CCDS23136.1
      UniProtKB/Swiss-Prot
      Q8BFU3
      Related
      ENSMUSP00000060941.6, ENSMUST00000058720.13
      Conserved Domains (1) summary
      cd16477
      Location:621665
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      45768067..45818209 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242496.3XP_011240798.1  RING finger protein 214 isoform X1

      See identical proteins and their annotated locations for XP_011240798.1

      Conserved Domains (1) summary
      cd16477
      Location:656700
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    2. XM_036154891.1XP_036010784.1  RING finger protein 214 isoform X7

      Conserved Domains (1) summary
      cd16477
      Location:393437
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    3. XM_036154890.1XP_036010783.1  RING finger protein 214 isoform X2

      Conserved Domains (1) summary
      cd16477
      Location:621665
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    4. XM_036154888.1XP_036010781.1  RING finger protein 214 isoform X1

      Conserved Domains (1) summary
      cd16477
      Location:656700
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    5. XM_030244319.1XP_030100179.1  RING finger protein 214 isoform X1

      Conserved Domains (1) summary
      cd16477
      Location:656700
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    6. XM_030244316.1XP_030100176.1  RING finger protein 214 isoform X3

      Conserved Domains (1) summary
      cd16477
      Location:601645
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    7. XM_030244320.1XP_030100180.1  RING finger protein 214 isoform X6

      Conserved Domains (1) summary
      cd16477
      Location:428472
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    8. XM_030244322.1XP_030100182.1  RING finger protein 214 isoform X7

      Conserved Domains (1) summary
      cd16477
      Location:393437
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    9. XM_030244318.2XP_030100178.1  RING finger protein 214 isoform X4

      Conserved Domains (1) summary
      cd16477
      Location:566610
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    10. XM_030244321.2XP_030100181.1  RING finger protein 214 isoform X6

      Conserved Domains (1) summary
      cd16477
      Location:428472
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    11. XM_030244315.2XP_030100175.1  RING finger protein 214 isoform X3

      Conserved Domains (1) summary
      cd16477
      Location:601645
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    12. XM_030244317.2XP_030100177.1  RING finger protein 214 isoform X4

      Conserved Domains (1) summary
      cd16477
      Location:566610
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    13. XM_036154889.1XP_036010782.1  RING finger protein 214 isoform X2

      Conserved Domains (1) summary
      cd16477
      Location:621665
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    14. XM_030244314.2XP_030100174.1  RING finger protein 214 isoform X1

      Conserved Domains (1) summary
      cd16477
      Location:656700
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
    15. XM_011242503.3XP_011240805.1  RING finger protein 214 isoform X5

      See identical proteins and their annotated locations for XP_011240805.1

      UniProtKB/Swiss-Prot
      Q8BFU3
      Conserved Domains (1) summary
      cd16477
      Location:501545
      RING-H2_RNF214; RING finger, H2 subclass, found in RING finger protein 214 (RNF214) and similar proteins
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