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    Ppan peter pan homolog [ Mus musculus (house mouse) ]

    Gene ID: 235036, updated on 27-Nov-2024

    Summary

    Official Symbol
    Ppanprovided by MGI
    Official Full Name
    peter pan homologprovided by MGI
    Primary source
    MGI:MGI:2178445
    See related
    Ensembl:ENSMUSG00000004100 AllianceGenome:MGI:2178445
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SSF1; A230087P06Rik
    Summary
    Predicted to enable rRNA binding activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within regulation of cell growth by extracellular stimulus. Predicted to be located in nucleus. Predicted to be part of preribosome, large subunit precursor. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to several human genes including PPAN (peter pan homolog). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in liver E14.5 (RPKM 44.9), ovary adult (RPKM 43.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ppan in Genome Data Viewer
    Location:
    9 A3; 9 7.66 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (20799471..20803475)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (20888175..20892179)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 39300 Neighboring gene shiftless antiviral inhibitor of ribosomal frameshifting Neighboring gene angiopoietin-like 6 Neighboring gene STARR-positive B cell enhancer ABC_E6717 Neighboring gene predicted gene, 24067 Neighboring gene predicted gene, 23008 Neighboring gene STARR-positive B cell enhancer ABC_E3817 Neighboring gene eukaryotic translation initiation factor 3, subunit G Neighboring gene DNA methyltransferase 1 Neighboring gene microRNA 7081

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of preribosome, large subunit precursor IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    suppressor of SWI4 1 homolog
    Names
    second-step splicing factor 1
    ssf-1
    suppressor of sterile four 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145610.2NP_663585.2  suppressor of SWI4 1 homolog

      See identical proteins and their annotated locations for NP_663585.2

      Status: VALIDATED

      Source sequence(s)
      AK039027, BB749945, CJ077201
      Consensus CDS
      CCDS22887.1
      UniProtKB/Swiss-Prot
      Q8BYM4, Q91YU8
      Related
      ENSMUSP00000004203.6, ENSMUST00000004203.6
      Conserved Domains (2) summary
      pfam04427
      Location:35285
      Brix; Brix domain
      cl00935
      Location:270341
      Brix; Brix domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      20799471..20803475
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)